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高尿酸血症与心血管疾病关系的研究进展

靳正逸 刘齐龙 胡佳琪 徐霞 高洁

内科理论与实践2025,Vol.20Issue(4):334-339,6.
内科理论与实践2025,Vol.20Issue(4):334-339,6.DOI:10.16138/j.1673-6087.2025.04.14

高尿酸血症与心血管疾病关系的研究进展

Advances in understanding the association between hyperuricemia and cardiovascular diseases

靳正逸 1刘齐龙 1胡佳琪 1徐霞 1高洁1

作者信息

  • 1. 海军军医大学第一附属医院风湿免疫科,上海 200433
  • 折叠

摘要

Abstract

Hyperuricemia is a disease caused by abnormal purine metabolism.The prevalence of hyperuricemia is increasing annually in China.Elevated uric acid levels not only lead to gout attacks but are also associated with the occurrence and development of cardiovascular diseases.Research indicates that hyperuricemia can facilitate the onset and progression of cardiovascular diseases through promoting inflammation,causing endothelial dysfunction,and over activating the renin-angiotensin-aldosterone system.This review discusses the association between hyperuricemia and various cardiovascular diseases,including coronary atherosclerosis,atrial fibrillation,hypertension,and heart failure.

关键词

高尿酸血症/心血管疾病/冠心病/心房颤动/心力衰竭/高血压

Key words

Hyperuricemia/Cardiovascular disease/Coronary atherosclerotic heart disease/Atrial fibrillation/Heart failure/Hypertension

分类

医药卫生

引用本文复制引用

靳正逸,刘齐龙,胡佳琪,徐霞,高洁..高尿酸血症与心血管疾病关系的研究进展[J].内科理论与实践,2025,20(4):334-339,6.

基金项目

海军军医大学第一附属医院临床新技术孵育项目(2024XB008) (2024XB008)

内科理论与实践

1673-6087

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