肿瘤预防与治疗2025，Vol.38Issue(10)：851-859,9.DOI:10.3969/j.issn.1674-0904.2025.10.001
肿瘤免疫中树突状细胞新型亚群的发现、作用机制及树突状细胞疫苗前景
Dendritic Cells in Tumor Immunity:Discovery of Novel Subsets,Func-tional Mechanisms,and Vaccine Applications
摘要
Abstract
Dendritic cells(DCs)are the most potent anti-gen-presenting cells,bridging innate and adaptive immunity.In recent years,increasing insights into the heterogeneity of DC subsets,their functional properties,and dynamic changes within the tumor microenvironment have brought significant at-tention to their roles in tumor initiation,progression,and immunotherapy.This review summarizes the phenotypic and func-tional features of newly identified DC subsets,emphasizing their roles and mechanisms in anti-tumor immunity.We further highlight recent advances in DC-based cancer vaccines and explore the potential of DCs in modulating tumor immunity.These findings provide a novel perspective for optimizing cancer immunotherapeutic strategies.关键词
树突状细胞/肿瘤/免疫治疗Key words
Dendritic cell/Tumor/Immunotherapy分类
医药卫生引用本文复制引用
杨雨桐,郑婷婷,黄功华..肿瘤免疫中树突状细胞新型亚群的发现、作用机制及树突状细胞疫苗前景[J].肿瘤预防与治疗,2025,38(10):851-859,9.基金项目
This study was supported by grants from Guangdong Basic and Applied Basic Research Foundation(No.2022A1515140062).广东省基础与应用基础研究基金项目(编号:2022A1515140062) （No.2022A1515140062）
