肿瘤预防与治疗2025，Vol.38Issue(10)：905-910,6.DOI:10.3969/j.issn.1674-0904.2025.10.008
老年胃肠肿瘤手术患者术后谵妄的发生率和危险因素:单中心观察性研究
Incidence and Risk Factors for Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal Tumor Surgery:A Single Center Observa-tional Study
摘要
Abstract
Objective:To investigate incidence and risk factors for postoperative delirium(POD)in elderly patients un-dergoing gastrointestinal tumor surgery.Methods:A total of 402 elderly patients who underwent elective laparoscopic gastro-intestinal tumor surgery in the Department of General Surgery at Zigong First People's Hospital from January 2021 to June 2023 were consecutively enrolled as the research subjects.The Confusion Assessment Method was used twice a day to evalu-ate the occurrence of POD within 7 days after surgery.The incidence of POD was observed.The research subjects were di-vided into two groups according to whether POD occurred.A logistic regression model was used to analyze the risk factors for POD in patients who had undergone laparoscopic gastrointestinal tumor surgery.Results:A total of 402 elderly patients who underwent laparoscopic surgery for gastrointestinal tumors were included.Of these,70 developed POD,yielding an incidence rate of 17.41％.POD occurred between days 1 and 7 after surgery,with the majority of cases(85.71％)occurring be-tween days 2 and 5.Multivariable logistic regression analysis identified the following as independent risk factors for POD in elderly patients undergoing laparoscopic gastrointestinal tumor surgery:age(OR=1.159,95％CI:1.063～1.263,P=0.001),alcoholism(OR=5.590,95％CI:1.843～19.212,P=0.003),diabetes(OR=5.103,95％CI:1.817～14.333,P=0.002),preoperative hemoglobin(OR=0.097,95％CI:0.952～0.996,P=0.019),first ambulation after surgery(OR=2.235,95％CI:1.779～2.808,P＜0.001),postoperative hospital stay(OR=1.922,95％CI:1.440～2.566,P＜0.001).Conclusion:Older age,alcoholism,diabetes,lower preoperative hemoglobin,delayed first ambulation,and a longer hospital stay are are independent risk factors for POD in elderly patients undergoing laparoscopic gastrointestinal tumor surgery.关键词
胃肠肿瘤/老年患者/术后谵妄/危险因素/Logistic回归模型Key words
Gastrointestinal tumor/Elderly patients/Postoperative delirium/Risk factors/Logistic regression model分类
医药卫生引用本文复制引用
马勇,方仕旭,李由,曹万龙,李洲..老年胃肠肿瘤手术患者术后谵妄的发生率和危险因素:单中心观察性研究[J].肿瘤预防与治疗,2025,38(10):905-910,6.基金项目
This study was supported by grants from Health Commission of Zigong(No.21yb004).自贡市卫生健康委科研课题(编号:21yb004) （No.21yb004）
