世界中医药2025，Vol.20Issue(14)：2531-2535,5.DOI:10.3969/j.issn.1673-7202.2025.14.018
肝性脑病患者中医证候特征分布规律及相关性研究
Characteristic Distribution Pattern and Correlation of TCM Syndromes in Patients with Hepatic Encephalopathy
摘要
Abstract
Objective:To analyze the pattern characteristics of syndromes in patients with hepatic encephalopathy(HE)and their correlations.Methods:A retrospective analysis was conducted on 1 043 HE patients admitted to the First Affiliated Hospital of Guangxi University of Chinese Medicine from January 2016 to June 2022.Demographic information,distribution of common tradi-tional Chinese medicine(TCM)diagnoses,TCM pattern types,and TCM pattern elements were analyzed.Results:Among the 1 043 patients,821(78.72％)were male and 222(21.28％)were female,with a male-to-female ratio of 3.7∶1.Age distribution was as follows:＜30 years,16 cases(1.53％);30 to 40 years,76 cases(7.28％);40 to 50 years,174 cases(16.68％);50 to 60 years,342 cases(32.79％);≥60 years,435 cases(41.7％).The top five TCM diagnoses were liver syncope(23.49％),liver cancer(21.00％),tympanites(16.68％),abdominal mass(15.05％),and jaundice(12.94％).The top five TCM syndrome types were liver qi stagnation(21.57％),liver-gallbladder dampness-heat(18.98％),qi stagnation and blood stasis(15.82％),phlegm-tur-bidity obstructing orifices(12.66％),and liver-kidney yin deficiency(11.41％).Young and middle-aged HE patients were mainly characterized by liver-qi stagnation,liver-gallbladder dampness-heat,and qi stagnation and blood stasis,while patients aged ≥60 years were mainly characterized by liver-kidney yin deficiency,accounting for 63.45％.Differences in TCM syndrome distribution among age groups were statistically significant(P=0.001).The most common syndrome elements were qi stagnation(37.93％),phlegm-dampness(21.96％),heat accumulation(19.94％),blood stasis(17.35％),turbid toxin(8.92％),yin deficiency(8.53％),cold condensation(7.48％),qi deficiency(6.90％),blood deficiency(3.93％),wind evil(3.07％),and others(3.07％).Conclusion:The predominant TCM syndrome in HE patients is liver qi stagnation,followed by liver-gallbladder damp-ness-heat.The occurrence of HE is related to gender and age,which also show a certain tendency in TCM syndrome distribution.关键词
肝性脑病/中医证型/证候要素/证候特征/肝气郁结Key words
Hepatic encephalopathy/TCM syndrome types/Syndrome elements/Syndrome characteristics/Liver qi stagnation分类
医药卫生引用本文复制引用
姚春,黄良江,黄国初,王萌,付蕾,张荣臻,龙富立,姚凡..肝性脑病患者中医证候特征分布规律及相关性研究[J].世界中医药,2025,20(14):2531-2535,5.基金项目
国家自然科学基金项目(82260899) （82260899）
广西重点研发计划项目(桂科AB22035076) （桂科AB22035076）
国家中医药管理局高水平中医药重点学科建设项目(姚春-中医内科学zyyzdxk-2023166) （姚春-中医内科学zyyzdxk-2023166）
姚春桂派中医大师传承工作室建设项目(GZY2024002) （GZY2024002）
疑难重症中医诊疗研究团队项目/广西中医药大学"桂派中医药传承创新团队"资助项目(2022A001) （2022A001）
广西研究生教育创新计划项目(YCSW2022343) （YCSW2022343）
