世界中医药2025，Vol.20Issue(14)：2543-2551,9.DOI:10.3969/j.issn.1673-7202.2025.14.020
急性冠脉综合征与脑梗死瘀毒病机指标和危险因素的分布特征研究
Distribution Characteristics of Pathogenesis Indicators and Risk Factors in Acute Coronary Syndrome and Cerebral Infarction with Blood Stasis and Toxin
摘要
Abstract
Objective:To investigate the risk factors and distribution of blood stasis and toxin pathogenesis indicators in acute coro-nary syndrome(ACS)and cerebral infarction(CI).Methods:A retrospective analysis was conducted on inpatients with ACS and CI admitted to Xiyuan Hospital,China Academy of Chinese Medical Sciences,from January 2020 to December 2022.Data were extrac-ted using Python programming.Chi-square test and t-test were applied to compare individual indicators between the two groups,and binary logistic regression was used to analyze the distribution characteristics of different indicators across groups.Results:A total of 3 418 patients were included,with a mean age of 68.5±11.7 years,including 1 938 males(56.7％)and 1 480 females(43.3％).There were 2 974 patients in the ACS group and 444 patients in the CI group.Compared with the CI group,the ACS group had higher prevalence of arteriosclerosis obliterans(ASO),hyperlipidemia(DLP),atrial fibrillation(AF),dry mouth and bit-ter taste,and old tongue,whereas the CI group was more closely associated with advanced age,diabetes mellitus(DM),constipa-tion,vertigo,and other factors.Conclusion:ACS and CI share multiple common risk factors and blood stasis and toxin pathogenesis indicators,including advanced age,DM,DLP,AF,dry mouth and bitter taste,and old tongue.However,the distribution of these fac-tors differs significantly between the two diseases.Identification of disease-specific risk factors and pathogenesis indicators is essen-tial for developing targeted prevention and control strategies to achieve more precise intervention and management.关键词
急性冠脉综合征/脑梗死/危险因素/瘀毒病机/逻辑回归Key words
Acute coronary syndrome/Cerebral infarction/Risk factors/Blood and stasis and toxin pathogenesis/Logistic regres-sion分类
医药卫生引用本文复制引用
张帆,曲华,赵伶俐,高铸烨..急性冠脉综合征与脑梗死瘀毒病机指标和危险因素的分布特征研究[J].世界中医药,2025,20(14):2543-2551,9.基金项目
国家自然科学基金项目(82274508)——清心解瘀方通过AMPK/mTORC1/ULK1信号通路调控线粒体自噬改善心梗后心室重构的机制研究 （82274508）
中国中医科学院科技创新工程重大攻关项目(CI2021A00920)——心血管病中医健康状态监测预警与防控模式示范研究 （CI2021A00920）
