医药导报2025，Vol.44Issue(11)：1804-1807,4.DOI:10.3870/j.issn.1004-0781.2025.11.014
药师对非瓣膜性心房颤动患者利伐沙班抗凝治疗处方的干预和分析
Pharmacists'Intervention and Analysis of Rivaroxaban Anticoagulant Therapy Prescriptions for Patients with Non-valvular Atrial Fibrillation
摘要
Abstract
Objective To evaluate the effect of clinical pharmacists in prescription intervention on rivaroxaban anticoagulation within non-valvular atrial fibrillation(NVAF)patients.Methods We collected 101 NVAF patients from January to June 2022 as the control group,and 125 NVAF patients from January to June 2023 after clinical pharmacists intervention as observation group.We audited the rivaroxaban prescriptions of the two groups of patients according to the evaluation criterion of appropriateness of rivaroxaban prescriptions for NVAF patients in our hospital.The rationality of rivaroxaban prescriptions,rivaroxaban anticoagulation-related thrombotic events,and bleeding events were compared between two groups.Results Clinical pharmacists provided 105 prescription interventions for observation group patients,of which 69(65.7%)were adopted and implemented by doctors.The rational rate of rivaroxaban prescription in the observation group was significantly increased(85.7%vs.16.8%,P<0.05).There were no statistical differences between the observation group and the control group in thrombotic events and major bleeding events during hospitalization(P>0.05),with a significant difference in thrombotic events 6 months after discharged(0.8%vs.7.9%,P<0.05).Conclusion The clinical pharmacist prescription intervention can improve the rational rate of rivaroxaban prescription and reduce the risk of thrombotic and bleeding events,which is an important measure to advance the safety and effectiveness of anticoagulant therapy.关键词
利伐沙班/非瓣膜性心房颤动/抗凝治疗/临床药师/处方干预Key words
Rivaroxaban/Non-valvular atrial fibrillation/Anticoagulation/Clinical pharmacist/Prescription intervention分类
医药卫生引用本文复制引用
柳浦青,王喻,陈静文,寿张轩..药师对非瓣膜性心房颤动患者利伐沙班抗凝治疗处方的干预和分析[J].医药导报,2025,44(11):1804-1807,4.基金项目
2022年浙江省卫生健康科技计划(2022KY235) （2022KY235）
2022年浙江省基础公益研究计划项目(LYY22H280001). （LYY22H280001）
