中国临床医学2025，Vol.32Issue(5)：755-760,6.DOI:10.12025/j.issn.1008-6358.2025.20250349
内镜下切除大直径十二指肠乳头肿瘤的临床疗效分析
Clinical efficacy analysis of endoscopic resection of large diameter duodenal papilla tumors
摘要
Abstract
Objective To explore the feasibility and clinical value of endoscopic resection of duodenal papilla tumors with a maximum diameter greater than 3 cm.Methods A retrospective analysis was conducted on the clinical data of all 12 patients who underwent endoscopic resection of duodenal papilla tumors at the Endoscopy Center of Zhongshan Hospital(Xuhui Hospital),Fudan University and Rongcheng Hospital of Traditional Chinese Medicine from September 2017 to May 2023.The size of the tumors all exceeded 3 cm.Results All 12 patients successfully completed the operation,with a complete resection rate of 91.7%(11/12)and an en-bloc resection rate of 91.7%(11/12).One patient experienced delayed bleeding due to unclosed wound during operation and received endoscopic hemostasis;11 cases underwent partial wound closure operation with pancreatic and biliary stent placement,without perforation or postoperative stenosis.Among them,2 cases(18.2%)experienced delayed bleeding and received endoscopic hemostasis treatment.After operation,1 case(8.3%)experienced nausea,vomiting,upper abdominal discomfort,and elevated blood amylase levels,who was later treated conservatively.During the mean follow-up period of 30.5(1.0-69.0)months,1 patient experienced recurrence and underwent surgical resection.Conclusions Endoscopic resection of duodenal papilla tumors can treat large diameter duodenal papilla tumors exceeding 3 cm,but postoperative complications may occur and require special attention.Postoperative placement of pancreatic and biliary stents and wound closure may reduce the incidence of complications.关键词
十二指肠乳头肿瘤/内镜下切除/大直径/疗效评估Key words
duodenal papilla tumor/endoscopic resection/large diameter/efficacy evaluation分类
医药卫生引用本文复制引用
张天彧,陈章涵,贺东黎,钟芸诗,王燕..内镜下切除大直径十二指肠乳头肿瘤的临床疗效分析[J].中国临床医学,2025,32(5):755-760,6.基金项目
国家自然科学基金(82273025).Supported by National Natural Science Foundation of China(82273025). （82273025）
