中国临床医学2025，Vol.32Issue(5)：776-784,9.DOI:10.12025/j.issn.1008-6358.2025.20250332
门静脉血栓对食管胃静脉曲张内镜治疗疗效影响的研究进展
Research advances of portal vein thrombosis affecting endoscopic treatment efficacy for esophagogastric varices
加依娜尔·波拉提汗 1王剑 2付钰 1马丽黎3
作者信息
- 1. 复旦大学附属中山医院内镜中心,上海 200032
- 2. 复旦大学附属中山医院消化科,上海 200032
- 3. 复旦大学附属中山医院内镜中心,上海 200032||复旦大学附属中山医院吴淞医院内镜中心,上海 200940
- 折叠
摘要
Abstract
Portal vein thrombosis(PVT)is a common complication in patients with liver cirrhosis,impacting the efficacy of endoscopic treatment for esophagogastric varices(EGV)by exacerbating portal hypertension and altering hemodynamics and coagulation function.This paper systematically reviews the pathogenesis of PVT,and its impact on the efficacy of endoscopic therapy for EGV.PVT is closely associated with early hemostatic failure post-endoscopic treatment,elevated rebleeding rate,and elevated long-term mortality.Although anticoagulation therapy facilitates partial thrombus recanalization and reduces portal pressure,its combination with endoscopic treatment requires careful consideration of the bleeding risk.Current clinical practice necessitates optimization of combined therapeutic strategies integrating anticoagulation and endoscopic treatment,complemented by personalized treatment approaches,to improve clinical outcomes.关键词
肝硬化/门静脉血栓/食管胃静脉曲张/内镜治疗/抗凝治疗Key words
liver cirrhosis/portal vein thrombosis/esophagogastric varices/endoscopic treatment/anticoagulation therapy分类
医药卫生引用本文复制引用
加依娜尔·波拉提汗,王剑,付钰,马丽黎..门静脉血栓对食管胃静脉曲张内镜治疗疗效影响的研究进展[J].中国临床医学,2025,32(5):776-784,9.
