中国实用儿科杂志2025，Vol.40Issue(9)：720-723,766,5.DOI:10.19538/j.ek2025090603
提高儿童风湿免疫性疾病的诊疗水平
Improving the diagnosis and treatment level of rheumatic and autoimmune diseases in children
摘要
Abstract
Remarkable progress has been made in diagnosis and treatment level of rheumatic and autoimmune diseases in children in recent years.On the diagnostic front,the advent of biomarker-driven disease stratification has revolutionized patient management by enabling early identification of high-risk individuals and facilitating personalized treatment plans.The expanding clinical application of genetic sequencing has particularly enhanced our comprehension of monogenic lupus and other prevalent childhood autoimmune disorders.Concurrently,diagnostic classification systems are undergoing continuous refinement to keep pace with the precision medicine paradigm shift.Therapeutic advancements have been equally transformative.Early,standardized intervention has emerged as a critical factor in preventing irreversible organ damage and optimizing long-term prognosis.Modern treatment strategies now feature increasingly targeted immunosuppressive regimens,while the accelerated development of biologic agents has substantially expanded the therapeutic arsenal for pediatric rheumatic diseases.Particularly promising are novel cellular therapies that show great potential in this evolving landscape.These collective developments underscore the growing importance of molecular-guided stratified diagnosis and tailored therapeutic interventions as fundamental components in elevating the standard of care for pediatric rheumatic and autoimmune disorders.关键词
风湿免疫性疾病/精准医学/个体化精准治疗Key words
rheumatic and immune diseases/precision medicine/personalized precision therapy分类
医药卫生引用本文复制引用
马明圣,周煜,宋红梅..提高儿童风湿免疫性疾病的诊疗水平[J].中国实用儿科杂志,2025,40(9):720-723,766,5.基金项目
国家重点研发计划(2021YFC2702001) （2021YFC2702001）
中央高水平医院临床科研专项(2022-PUMCH-B-079) （2022-PUMCH-B-079）
