中国实用儿科杂志2025，Vol.40Issue(9)：734-740,7.DOI:10.19538/j.ek2025090606
儿童慢性无菌性骨髓炎的诊断与治疗
Diagnosis and management of chronic nonbacterial osteomyelitis in children
摘要
Abstract
Chronic nonbacterial osteomyelitis is a rare autoinf-lammatory bone disease characterized by recurrent nonbacterial osteomyelitis.The lesions mainly affect long bones,spine,and anterior chest wall,presenting as nocturnal bone pain caused by single or multiple bone marrow inflammations.The disease progresses chronically and insidiously,with significant heterogeneity in clinical manifestations.Delayed treatment can lead to irreversible bone destruction.This article reviews and summarizes the disease from aspects such as pathogenesis,clinical manifestations,diagnostic criteria,differential diagnosis,and treatment strategies,aiming to improve pediatricians' understanding of the disease and provide a theoretical basis for standardized diagnosis and treatment.关键词
慢性无菌性骨髓炎/慢性复发性多灶性骨髓炎/自身炎症性骨病Key words
chronic nonbacterial osteomyelitis/chronic recurrent multifocal osteomyelitis/autoinflammatory bone disease分类
医药卫生引用本文复制引用
马乐,樊志丹,黄娜,俞海国..儿童慢性无菌性骨髓炎的诊断与治疗[J].中国实用儿科杂志,2025,40(9):734-740,7.基金项目
国家自然科学基金项目(82271838) （82271838）
国家重点研发计划项目(2021YFC2702000) （2021YFC2702000）
