中国药物经济学2025，Vol.20Issue(10)：75-79,5.DOI:10.12010/j.issn.1673-5846.2025.10.016
某医院283份药品不良反应报告分析与预防措施
Analysis and Preventive Measures of 283 Adverse Drug Reactions Reports in A Hospital
摘要
Abstract
Objective To explore the characteristics and patterns of drug adverse reactions(ADR)in a tertiary hospital to provide a reference for ensuring patient medication safety.Methods A total of 283 ADR reports submitted and evaluated by the First Affiliated Hospital of Dali University in 2023 were retrieved from the National ADR Surveillance System.A retrospective analysis method was adopted,and statistical analysis was conducted according to the patients'age,gender,ADR type,administration route causing ADR,type of drugs causing ADR,organs/systems involved in ADR,clinical manifestations and outcomes.Results Among the 283 ADR patients,those over 40 years old had a higher ADR occurrence rate(242 cases,85.51%);females(50.88%)outnumbered males(49.12%);the predominant ADR types were general ADRs(173 cases,61.13%)and severe ADRs(75 cases,26.5%);the main administration routes were intravenous infusion(141 cases,49.82%)and oral administration(109 cases,38.52%);drugs causing ADRs included antitumor drugs(22.63%),cardiovascular drugs(15.26%),and anti-infective drugs(13.16%);the primary affected organs/systems were the skin,blood and hematopoietic system,and digestive system;Among the 283 patients with ADR,227 cases(80.21%)improved.Conclusion It is important to enhance ADR monitoring in elderly patients,select appropriate administration routes,and focus on antitumor,cardiovascular,and anti-infective drugs to reduce ADR incidence and ensure clinical medication safety.关键词
药品/不良反应监测/用药安全Key words
Drugs/Adverse reaction monitoring/Medication safety分类
医药卫生引用本文复制引用
赵燕菊,施娟,杨学英,赵顺芳..某医院283份药品不良反应报告分析与预防措施[J].中国药物经济学,2025,20(10):75-79,5.基金项目
大理大学第一附属医院临床医学学科队伍建设项目(DFYYB2024031) （DFYYB2024031）
大理市科技计划项目(2023KBG077) （2023KBG077）
