中国医学创新2025，Vol.22Issue(29)：5-9,5.DOI:10.3969/j.issn.1674-4985.2025.29.002
润肺膏联合注射用头孢噻肟钠对老年CAP患者症状消退时间及炎症因子水平的影响
Influence of Runfei Ointment Combined with Cefotaxime Sodium for Injection on Symptom Regression Time and Inflammatory Factors Levels in Elderly Patients with CAP
摘要
Abstract
Objective:To study the influence of Runfei Ointment combined with Cefotaxime Sodium for Injection on the symptom regression time and levels of inflammatory factors in elderly patients with community-acquired pneumonia(CAP).Method:Eighty elderly CAP patients in Nanchang 334 Hospital from January 2023 to September 2024 were selected and divided into single group(treated with Cefotaxime Sodium,n=40)and combined group(Runfei Ointment on the basis of single group,n=40)by random envelope method.After 2 weeks of treatment,the efficacy,symptom regression time,inflammatory factors[serum amyloid A(SAA),CRP and IL-6]and occurrence of adverse reactions were evaluated in the two groups.Result:The total effective rate of treatment in combined group was 97.50%,which was higher than 85.00%in single group(P<0.05).The cough and expectoration regression time,fever abatement time and disappearance time of pulmonary rales in combined group were(4.02±0.66),(2.46±0.61)and(4.86±0.74)d,which were earlier than(4.74±0.79),(3.22±0.69)and(6.24±0.97)d in single group(P<0.05).After treatment,the levels of SAA,CRP and IL-6 in both groups were decreased,and the levels in combined group[(7.42±1.02)mg/L,(7.32±1.28)mg/L and(4.86±1.02)pg/mL]were lower than(8.25±1.56)mg/L,(9.05±2.71)mg/L and(5.62±1.13)pg/mL in single group(P<0.05).There was no statistical difference in the occurrence of adverse reactions between groups(P>0.05).Conclusion:Runfei Ointment combined with Cefotaxime Sodium for Injection has significant efficacy in the treatment of elderly CAP.It can effectively shorten the clinical symptom regression time and improve the inflammatory response of patients,and it will not aggravate adverse reactions,with high safety.关键词
润肺膏/头孢噻肟钠/老年患者/社区获得性肺炎/炎症因子Key words
Runfei Ointment/Cefotaxime Sodium/Elderly patients/Community-acquired pneumonia/Inflammatory factors引用本文复制引用
高洁,邓雪颖..润肺膏联合注射用头孢噻肟钠对老年CAP患者症状消退时间及炎症因子水平的影响[J].中国医学创新,2025,22(29):5-9,5.基金项目
江西省卫生健康委科技计划项目(2023JX11356) （2023JX11356）
