摘要
Abstract
Objective:To explore the effects of modified meibomian gland massage combined with Sodium Hyaluronate on corneal stability and tear film function in patients with meibomian gland dysfunction(MGD)-related dry eye.Method:A total of 90 patients with MGD-related dry eye admitted to Department of Ophthalmology,the Second Affiliated Hospital of Hunan University of Chinese Medicine from December 2022 to May 2024 were prospectively selected and divided into massage group(n=45)and routine group(n=45)according to the random number table.The routine group was given Sodium Hyaluronate eye drops treatment,massage group was given modified meibomian gland massage treatment on this basis.The corneal stability(corneal fluorescein staining score),tear film function[breakup time of tear film(BUT),Schirmer Ⅰ test(SⅠt)],meibomian gland function[meibomian gland yielding liquid secretion(MGYLS)],therapeutic effect and adverse reactions were compared between the two groups.Result:The corneal fluorescein staining score and MGYLS score in massage group and routine group after treatment were lower than those before treatment,and the corneal fluorescein staining score and MGYLS score in massage group were lower than those in routine group(P<0.05).The BUT and SⅠt in both groups after treatment were longer than those before treatment,and the BUT and SⅠt in massage group were longer than those in routine group(P<0.05).The total effective rate of massage group was higher than that of routine group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the routine group and the massage group(P>0.05).Conclusion:Modified meibomian gland massage combined with Sodium Hyaluronate treatment can improve corneal stability and tear film function in patients with MGD-related dry eye,promote the recovery of meibomian gland function,enhance therapeutic effect,and has good safety.关键词
改良睑板腺按摩/玻璃酸钠/睑板腺功能障碍/干眼/角膜稳定性/泪膜功能Key words
Modified meibomian gland massage/Sodium Hyaluronate/Meibomian gland dysfunction/Dry eye/Corneal stability/Tear film function
