首页|期刊导航|结合医学学报（英文版）|Huachansu injection enhances anti-colorectal cancer efficacy of irinotecan and alleviates its induced intestinal toxicity through upregulating UGT1A1-OATP1B3 expression in vitro and in vivo

Huachansu injection enhances anti-colorectal cancer efficacy of irinotecan and alleviates its induced intestinal toxicity through upregulating UGT1A1-OATP1B3 expression in vitro and in vivo

Bo Jiang Zhao-yang Meng Yu-jie Hu Jun-jun Chen Ling Zong Ling-yan Xu Xiang-qi Zhang Jing-xian Zhang Yong-long Han

结合医学学报（英文版）2025，Vol.23Issue(5)：576-590,15.

结合医学学报（英文版）2025，Vol.23Issue(5)：576-590,15.DOI:10.1016/j.joim.2025.06.006

Huachansu injection enhances anti-colorectal cancer efficacy of irinotecan and alleviates its induced intestinal toxicity through upregulating UGT1A1-OATP1B3 expression in vitro and in vivo

Bo Jiang ¹Zhao-yang Meng ²Yu-jie Hu ³Jun-jun Chen ³Ling Zong ³Ling-yan Xu ³Xiang-qi Zhang ³Jing-xian Zhang ³Yong-long Han²

作者信息

1. Shanghai Changning Mental Health Center,East China Normal University,Shanghai 200335,China||Department of Pharmacy,Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China
2. Department of Pharmacy,Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China||College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China
3. Department of Pharmacy,Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200233,China
折叠

摘要

关键词

Huachansu injection/Bufadienolides/UGT1A1/Irinotecan/Colorectal cancer

Key words

Huachansu injection/Bufadienolides/UGT1A1/Irinotecan/Colorectal cancer

引用本文复制引用

Bo Jiang,Zhao-yang Meng,Yu-jie Hu,Jun-jun Chen,Ling Zong,Ling-yan Xu,Xiang-qi Zhang,Jing-xian Zhang,Yong-long Han..Huachansu injection enhances anti-colorectal cancer efficacy of irinotecan and alleviates its induced intestinal toxicity through upregulating UGT1A1-OATP1B3 expression in vitro and in vivo[J].结合医学学报（英文版）,2025,23(5):576-590,15.

基金项目

The authors gratefully acknowledge the award from Pudong Commission of Science and Technology and Economy and Informa-tization(No.PKJ2019-Y04),Pudong New Area Health Commission Health Research Project(No.PW2021E-03),and Traditional Chi-nese Medicine Inheritance and Scientific and Technological Innova-tion Project of Shanghai Municipal Health Commission(No.ZYCC2019017)for financial support of this study. （No.PKJ2019-Y04）

结合医学学报（英文版）

ISSN：2095-4964

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