福建师范大学学报（自然科学版）2025，Vol.41Issue(6)：101-110,121,11.DOI:10.12046/j.issn.1000-5277.2024030046
基于纳米酶的生物医学研究进展
Progress in Biomedical Research Based on Nanozymes
摘要
Abstract
Nanozymes are a class of nanomaterials with enzyme-like properties.Due to their controllable high catalytic activity,high stability,low cost,and easy storage,they have flourished as substitutes for natural enzymes over the past decade.With the rapid advancements of nanoscience and nanotechnology,nanozymes are expected to directly replace traditional enzymes by mimicking and modifying the active centers of natural enzymes.To date,hundreds of nanomaterials have been found to mimic the catalytic activity of various enzymes,such as peroxidase,oxidase,glucose oxi-dase,catalase,glutathione peroxidase,and superoxide dismutase.Due to their unique physico-chemical properties,nanozymes exhibit broad application prospects in biomedical fields.In this re-view,we summarize the definition,classification,and properties of nanozymes,as well as their latest research and applications in biomedicine.We also discuss their mechanisms of action and spe-cific applications in biosensing,bioimaging,and biotherapy,and provide an outlook on future challenges.关键词
纳米酶/类酶活性/生物催化/生物医学/生物传感/生物成像/生物治疗Key words
nanozymes/enzyme-like activity/biological catalysis/biomedicines/biosensing/bioimaging/biotherapy分类
化学引用本文复制引用
王淏,陈旖,徐菲,尚谦实,张颖,项雷文,罗志敏..基于纳米酶的生物医学研究进展[J].福建师范大学学报（自然科学版）,2025,41(6):101-110,121,11.基金项目
国家自然科学基金面上项目(22275096) （22275096）
