分析测试学报2025，Vol.44Issue(11)：2256-2264,9.DOI:10.12452/j.fxcsxb.250410281
AHP-CRITIC结合BP-ANN的归志方提取工艺优化研究
Optimization of Extraction Process for Guizhi Prescription Based on the Integration of AHP-CRITIC and BP-ANN
摘要
Abstract
The extraction process of Guizhi prescription was optimized by analytic hierarchy process-criteria importance through intercriteria correlation hybrid weighting method(AHP-CRITIC)and backpropagation artificial neural network(BP-ANN).The weight coefficients determined by the AHP-CRITIC method for ginsenoside Rg1,ginsenoside Re,ginsenoside Rb1,tenuifolin,paeoniflorin,ferulic acid and extract yield were 0.190 7,0.217 5,0.234 1,0.089 4,0.119 5,0.087 5,and 0.061 3,respectively.The optimal extraction process was as follows:10 times the solvent vol-ume,2 hours per extraction,and 3 extraction cycles.The network prediction results of BP-ANN test samples were consistent with the orthogonal test results.In addition,AHP-CRITIC and BP-ANN integrating analysis suggested that the extraction efficacy of another extraction process(10 times the solvent volume,1 hour per extraction,and 2 extraction cycles)showed no statistically signifi-cant difference with the optimal extraction process,thus the energy conserved extraction process is more suitable for the large-scale production.This study provides a reference for the further develop-ment and large-scale production of Guizhi prescription,moreover,it builds a reliable methodology basis for modernizing extraction process method of traditional Chinese medicines.关键词
归志方/层次分析-指标相关性权重确定的组合加权法(AHP-CRITIC)/反向传播人工神经网络(BP-ANN)/提取工艺/正交试验设计Key words
Guizhi prescription/analytic hierarchy process-criteria importance through intercrite-ria correlation hybrid weighting method(AHP-CRITIC)/backpropagation artificial neural network(BP-ANN)/extraction process/orthogonal experimental design分类
化学化工引用本文复制引用
李月婷,肖红斌,魏祖英,王腾腾,程超,谭颖,许一帆,霍滢滢,高家乐,刘洁..AHP-CRITIC结合BP-ANN的归志方提取工艺优化研究[J].分析测试学报,2025,44(11):2256-2264,9.基金项目
国家自然科学基金面上项目(82173957) （82173957）
国家自然科学基金青年基金项目(82204599) （82204599）
国家中医药管理局高水平中医药重点学科(中药分析学)建设项目(zyyzdxk-2023265) （中药分析学）
