分析测试学报2025，Vol.44Issue(11)：2376-2382,7.DOI:10.12452/j.fxcsxb.25011322
基于便携式质谱技术的中药材中啶虫脒与多菌灵测定方法研究
Determination of Acetamiprid and Carbendazim in Chinese Medicinal Materials Based on Portable Mass Spectrometry Technique
摘要
Abstract
In this study,a rapid detection method based on portable mass spectrometry technology for the detection of pesticide residues in Chinese medicinal materials(CMM)was established.No-toginseng Radix et Rhizoma,Lonicerae Japonicae Flos and Lycii Fructus were used as detection ob-jects,acetamiprid and carbendazim were used as detection indicators to investigate the sensitivity and accuracy of the established method.The results indicated that by using a direct extraction com-bined with hydrophilic and lipophilic balance(HLB)solid-phase extraction column clean-up method,acetamiprid and carbendazim showed good linearity(r＞0.99)in the ranges of 1.0-40 mg/kg and 0.125-5.0 mg/kg,respectively.The detection limits(LOD)for acetamiprid and carbendazim were 0.30 mg/kg and 0.05 mg/kg,while the quantitation limits(LOQ)for carbendazim and carbendazim were 1.0 mg/kg and 0.125 mg/kg,respectively.The method achieved recoveries ranging from 72.8％to 95.3％,with relative standard deviations(RSDs)between 10％and 34％.The portable mass spectrometry was used to determine acetamiprid and carbendazim in Notoginseng Radix et Rhi-zoma,Lonicerae Japonicae Flos,Lycii Fructus,validated by liquid chromatography-tandem mass spectrometry(LC-MS/MS).The results were basically consistent,which indicated that portable mass spectrometry can meet the daily detection needs of acetamiprid and carbendazim in CMM.关键词
便携式质谱/中药材/农药残留/快速检测Key words
portable mass spectrometry/Chinese medicinal materials/pesticide residues/rapid detection分类
化学引用本文复制引用
周婷婷,刘芫汐,张婉茹,金红宇,魏锋,王莹..基于便携式质谱技术的中药材中啶虫脒与多菌灵测定方法研究[J].分析测试学报,2025,44(11):2376-2382,7.基金项目
国家重点研发计划项目(2023YFC3504103) （2023YFC3504103）
国家药监局药品监管科学全国重点实验室第一批开放课题(2023SKLDRS0103) （2023SKLDRS0103）
