分析化学2025，Vol.53Issue(10)：1631-1641,11.DOI:10.19756/j.issn.0253-3820.251192
电化学法制备分子印迹表面增强拉曼散射芯片用于双酚A的高选择性检测
Electrochemical Fabrication of Molecularly Imprinted Surface-enhanced Raman Scattering Chips for Highly Selective Detection of Bisphenol A
摘要
Abstract
A portable molecularly imprinted(MIP)surface-enhanced Raman scattering(SERS)chip was fabricated via a green electrochemical approach for highly selective detection of bisphenol A(BPA).This MIP-AuNP/UIO-66/SPE sensor was fabricated through a single-step co-deposition process.The process involved electropolymerization onto a UIO-66 modified screen-printed electrode(SPE),by usingo-phenylenediamine(OPD)as functional monomer and BPA as template,and simultaneously electro-reduction generated gold nanoparticles(AuNPs),which served as the SERS-active substrate.Ultimately,this one-step method formed a three-dimensional porous architecture on the electrode surface.Under 785 nm laser excitation,the sensing chip exhibited a highly sensitive SERS response towards BPA.The intensity of its characteristic peak at 850 cm-1 showed a good linear relationship with logarithm of BPA concentration in the range of 1.0×10-10 to 1.0×10-6 mol/L,with a detection limit of 1.0×10-12 mol/L.More importantly,the fabricated chips maintained highly selective binding affinity for BPA in water samples even in the presence of structural analogs bisphenol F(BPF)and bisphenol S(BPS).When the chip was applied to detection of BPA in water samples from plastic bottle and paper cup,the recovery rates ranged from 94.0%to 103.0%with relative standard deviations(RSD)less than 4.7%.The developed chip offered a highly sensitive and selective solution for detection of trace BPA in complex water samples.关键词
分子印迹聚合物/电化学聚合/表面增强拉曼散射/双酚AKey words
Molecularly imprinted polymers/Electropolymerization/Surface-enhanced Raman scattering/Bisphenol A引用本文复制引用
刘姝辰,田满妹,吴舟雅,李原婷..电化学法制备分子印迹表面增强拉曼散射芯片用于双酚A的高选择性检测[J].分析化学,2025,53(10):1631-1641,11.基金项目
国家自然科学基金项目(No.21707092)资助. Supported by the National Natural Science Foundation of China(No.21707092). （No.21707092）
