高等学校化学学报2025，Vol.46Issue(11)：80-91,12.DOI:10.7503/cjcu20250210
十二烷基磺酸钠在正丙醇/水混合溶液中囊泡的形成及性能
Formation and Properties of Sodium Dodecyl Sulfonate Vesicles in n-Propanol/Water Mixed Solutions
摘要
Abstract
The self-assembly behavior of sodium dodecyl sulfonate(SDS)in n-propanol(NPP)/water mixed solutions was studied using methods such as dynamic light scattering(DLS),transmission electron microscopy(TEM),small-angle X-ray scattering(SAXS),and Fourier transform infrared spectroscopy(FTIR).Experimental results demonstrated that the introduction of NPP significantly enhanced the solubility of SDS.In the 50%(mass ratio)NPP/water mixed solvent,the solubility of SDS reached 225.71 g/L,representing a 93-fold increase compared to the pure water system(2.42 g/L).The study reveals that in the isotropic phase of the SDS/NPP/H2O ternary system,besides the typical micellar structure,vesicle aggregates are also observed.As the NPP content progressively increased,the vesicular structures gradually transformed into micelles.When the NPP content exceeded 50%(mass ratio),the aggregates within the system primarily existed as micelles.FTIR spectral analysis confirmed the formation of hydrogen bonds between SDS and NPP molecules(—S=O…H—O—),the"water bridge"and"cation(Na+)bridge"(—SO3-…Na+…—SO3-)between SDS molecules played crucial roles.These interactions effectively mitigated the electrostatic repulsion between the anionic headgroups,which is pivotal for the formation of the SDS/NPP vesicular phase.Furthermore,SAXS and atomic force microscopy(AFM)confirmed the presence of an interdigitated structure of alkyl chains between two leaflets configuration within the vesicle bilayer membranes,with an interdigitated degree of 28.57%.This highly interdigitated structure of alkyl chains between two leaflets is also an intrinsic factor contributing to the formation and stability of the SDS/NPP vesicles.The SDS/NPP vesicles exhibit excellent stability under various conditions,including long-term storage,high-temperature treatment,and freeze-thaw cycles.Furthermore,they exhibit a notable capacity for encapsulating hydrophilic dyes such as calcein.Additionally,the vesicle membrane demonstrates,permeability towards OH-ions,and the transmembrane perme-ation process conforms to a first-order kinetic model.This study could deepen the understanding of the aggregation behavior of single-chain amphiphiles and provide valuable insights for the practical application of single-chain amphi-philic molecule vesicles.关键词
囊泡/十二烷基磺酸钠/正丙醇/自组装Key words
Vesicle/Sodium dodecyl sulfonate/n-Propanol/Self-assembly分类
化学化工引用本文复制引用
吴燕茹,李安明,高美华,庄文昌..十二烷基磺酸钠在正丙醇/水混合溶液中囊泡的形成及性能[J].高等学校化学学报,2025,46(11):80-91,12.基金项目
国家自然科学基金(批准号:22302165)和江苏省双创博士计划项目(批准号:JSSCBS20221588)资助. Supported by the National Natural Science Foundation of China(No.22302165)and the Jiangsu Provincial Double Innovation Doctoral Plan,China(No.JSSCBS20221588). （批准号:22302165）
