国际口腔科学杂志(英文版)2025,Vol.17Issue(5):677-691,15.DOI:10.1038/s41368-025-00384-6
Single-cell transcriptomics identifies PDGFRA+progenitors orchestrating angiogenesis and periodontal tissue regeneration
Single-cell transcriptomics identifies PDGFRA+progenitors orchestrating angiogenesis and periodontal tissue regeneration
Jianing Liu 1Nan Zhang 1Hao Wang 2Ji Chen 3Peisheng Liu 2Jiongyi Tian 2Jiexi Liu 2Yuru Gao 2Haokun Xu 2Chao Ma 2Shengfeng Bai 2Junxi He 1Yubohan Zhang 1Yan Jin 2Chenxi Zheng 2Bingdong Sui 2Fang Jin 4Ziqi Zhang 1Lu Liu 1Yuan Cao 1Xiaohui Zhang 1Xinyue Cai 5Xinyan Luo 2Xiao Lei1
作者信息
- 1. State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi International Joint Research Center for Oral Diseases,Center for Tissue Engineering,School of Stomatology,The Fourth Military Medical University,Xi'an,China||State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Clinical Research Center for Oral Diseases,Department of Orthodontics,School of Stomatology,The Fourth Military Medical University,Xi'an,China
- 2. State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi International Joint Research Center for Oral Diseases,Center for Tissue Engineering,School of Stomatology,The Fourth Military Medical University,Xi'an,China
- 3. State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture,Department of Oral Implantology,School of Stomatology,The Fourth Military Medical University,Xi'an,China
- 4. State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Clinical Research Center for Oral Diseases,Department of Orthodontics,School of Stomatology,The Fourth Military Medical University,Xi'an,China
- 5. State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi International Joint Research Center for Oral Diseases,Center for Tissue Engineering,School of Stomatology,The Fourth Military Medical University,Xi'an,China||State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Clinical Research Center for Oral Diseases,Department of Preventive Dentistry,School of Stomatology,The Fourth Military Medical University,Xi'an,China
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Jianing Liu,Nan Zhang,Hao Wang,Ji Chen,Peisheng Liu,Jiongyi Tian,Jiexi Liu,Yuru Gao,Haokun Xu,Chao Ma,Shengfeng Bai,Junxi He,Yubohan Zhang,Yan Jin,Chenxi Zheng,Bingdong Sui,Fang Jin,Ziqi Zhang,Lu Liu,Yuan Cao,Xiaohui Zhang,Xinyue Cai,Xinyan Luo,Xiao Lei..Single-cell transcriptomics identifies PDGFRA+progenitors orchestrating angiogenesis and periodontal tissue regeneration[J].国际口腔科学杂志(英文版),2025,17(5):677-691,15.基金项目
This work was supported by grants from the National Key Research and Development Program of China(2022YFA1104400),the National Natural Science Foundation of China(82170988,82371020,82301028,82401201,82471011),the Young Science and Technology Rising Star Project of Shaanxi Province(2024ZC-KJXX-122),the China Postdoctoral Science Foundation(BX20230485),the Project of State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration(2024MS04),the Shaanxi Provincial Health Research and Innovation Platform Construction Plan(2024PT-04),the"Rapid Response"Research projects(2023KXKT017 and 2023KXKT090),and the Intramural Research Program project founded by Fourth Military Medical University(2024QMJJ008).We would like to express gratitude to Shanghai OE Biotech Co.,Ltd,for the technical support in carrying out scRNA-seq and analysis. (2022YFA1104400)