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Ultrawideband high density polymer-based spherical array for real-time functional optoacoustic micro-angiography

Pavel V.Subochev Mikhail D.Proyavin Roman I.Ovsyannikov Anatoly G.Sanin Mikhail Y.Kirillin Francisco Montero de Espinosa Ilya V.Turchin Daniel Razansky Xosé Luís Deán-Ben Zhenyue Chen Maxim B.Prudnikov Vladimir A.Vorobev Alexey A.Kurnikov Anna G.Orlova Anna S.Postnikova Alexey V.Kharitonov

光：科学与应用（英文版）2025，Vol.14Issue(9)：2489-2502,14.

光：科学与应用（英文版）2025，Vol.14Issue(9)：2489-2502,14.DOI:10.1038/s41377-025-01894-y

Ultrawideband high density polymer-based spherical array for real-time functional optoacoustic micro-angiography

Pavel V.Subochev ¹Mikhail D.Proyavin ¹Roman I.Ovsyannikov ¹Anatoly G.Sanin ¹Mikhail Y.Kirillin ¹Francisco Montero de Espinosa ²Ilya V.Turchin ¹Daniel Razansky ³Xosé Luís Deán-Ben ⁴Zhenyue Chen ⁵Maxim B.Prudnikov ¹Vladimir A.Vorobev ¹Alexey A.Kurnikov ¹Anna G.Orlova ¹Anna S.Postnikova ¹Alexey V.Kharitonov¹

作者信息

1. Institute of Applied Physics,Russian Academy of Sciences,Nizhny Novgorod,Russia
2. Instituto de Tecnologías Físicas y de la Información-CSIC,Madrid,Spain
3. Institute of Pharmacology and Toxicology and Institute for Biomedical Engineering,Faculty of Medicine,University of Zurich,Zurich,Switzerland||Institute for Biomedical Engineering,Department of Information Technology and Electrical Engineering,ETH Zurich,Zurich,Switzerland||Institute for Biological and Medical Imaging,Helmholtz Center Munich,Neuherberg,Germany
4. Institute of Pharmacology and Toxicology and Institute for Biomedical Engineering,Faculty of Medicine,University of Zurich,Zurich,Switzerland||Institute for Biomedical Engineering,Department of Information Technology and Electrical Engineering,ETH Zurich,Zurich,Switzerland
5. Institute of Pharmacology and Toxicology and Institute for Biomedical Engineering,Faculty of Medicine,University of Zurich,Zurich,Switzerland||Institute for Biomedical Engineering,Department of Information Technology and Electrical Engineering,ETH Zurich,Zurich,Switzerland||Institute of Precision Optical Engineering,School of Physics Science and Engineering,Tongji University,Shanghai,China
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Pavel V.Subochev,Mikhail D.Proyavin,Roman I.Ovsyannikov,Anatoly G.Sanin,Mikhail Y.Kirillin,Francisco Montero de Espinosa,Ilya V.Turchin,Daniel Razansky,Xosé Luís Deán-Ben,Zhenyue Chen,Maxim B.Prudnikov,Vladimir A.Vorobev,Alexey A.Kurnikov,Anna G.Orlova,Anna S.Postnikova,Alexey V.Kharitonov..Ultrawideband high density polymer-based spherical array for real-time functional optoacoustic micro-angiography[J].光：科学与应用（英文版）,2025,14(9):2489-2502,14.

基金项目

The system integration,experimental validation,and image processing were supported by the Swiss National Science Foundation(310030_192757)and the European Research Council(ERC-2015-CoG-682379).The development of the ultra-wldeband ultrasonic antenna and the in vivo optoacoustic experiments were supported by the grants from the Russian Science Foundation(18-45-06006)and the Helmholtz Association(HRSF-0020).The development of numerical algorithms for enhancement of angiographic optoacoustic images was partially supported by the grant from the Russian Science Foundation(19-75-10055) （310030_192757）

The authors are grateful to Dr.Ivan Pelivanov(University of Washington),Dr.Andrew Hurrell and Terry Gill(Precision Acoustics),Dr.Michael Jaeger and Prof.Martin Frenz(University of Bern),Prof.Yoshifumi Saijo(Tohoku University),Dr.James Guggenheim and Prof.Paul Beard(University College London),Dr.Vassili Ivanov(PhotoSound),Prof.Alexander Karabutov(Moscow State University),Dr.Kazuto Kobayashi(Honda Electronics),Dr.Xuecang Geng(Blatek),Dr.Shihai Zhang(Poly-K),and Dr.Francois Bauer(Piézotech S.A.S.)for useful discussions and to Ivan Antonov,Valentina Kotomina,Dr.Alexey Mikhailov,and Prof.Vladimir Chuvildeev(Nizhny Novgorod Research Institute for Physics and Technology)for technological assistance. （University of Washington）

光：科学与应用（英文版）

ISSN：2095-5545

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