国际口腔医学杂志2025，Vol.52Issue(6)：738-747,10.DOI:10.7518/gjkq.2025065
外伤年轻恒牙行牙髓再生治疗的研究进展
Research progress in regenerative endodontics for traumatized immature permanent teeth
摘要
Abstract
Trauma can easily lead to pulp necrosis and periapical periodontitis in immature permanent teeth,and the roots then stop developing.At this time,immature permanent teeth are characterized by open apical foramina,thin root ca-nal walls,and short roots that affect their retention and function in the oral cavity.Regenerative endodontics is a treatment that can promote the continuous development of the roots of immature permanent teeth.This procedure has significant clinical significance in the healing of periapical lesions and the closure of apical foramina as well as in increasing the length of the roots and the thickness of the root canal walls.Although most studies reported a high success rate for this procedure,failure may occur,including persistent root resorption and persistent periapical inflammation.In this paper,we provide a systematic review of regenerative endodontics for traumatized immature permanent teeth in terms of the treat-ment process,biological rationale,clinical outcomes,and analysis of cases of treatment failure to provide the-oretical basis for clinicians.关键词
牙外伤/年轻恒牙/牙髓坏死及根尖周炎/牙髓再生治疗Key words
dental trauma/immature permanent teeth/pulp necrosis and periapical periodontitis/re-generative endodontics procedure分类
口腔医学引用本文复制引用
张书旸,胡顺佳怡,戚琳珑,梁筱瑶,邓淑丽..外伤年轻恒牙行牙髓再生治疗的研究进展[J].国际口腔医学杂志,2025,52(6):738-747,10.基金项目
Grants from"Pioneer"and"Leading Goose"Research and Development Program in Zhejiang Province(2022C03060) 浙江省"尖兵""领雁"研发攻关计划(2022C03060) （2022C03060）
