家畜生态学报2025，Vol.46Issue(10)：22-27,6.DOI:10.3969/j.issn.1673-1182.2025.10.004
贵州地方猪肝脏脂质代谢及相关基因表达模式分析
Analysis of Lipid Metabolism and Related Gene Expression Patterns in Livers of Guizhou Local Pigs
摘要
Abstract
To explore the potential regulatory mechanisms of meat quality traits in local pig breeds from Guizhou Province,this study compared the differences in average backfat thickness,liver lipid me-tabolism-related indicators,and the expression levels of lipid metabolism-related genes between Guizhou local pigs(Jiangkou Luobo pigs,Nuogu pigs,Kele pigs,Baixi pigs,Guanling pigs,Congjiang Xiang pigs,Qiandong Spotted pigs and Qianbei Black pigs)and Yorkshire pigs.Among the local breeds,Jiangkou Luobo pigs exhibited the thickest backfat,while Congjiang Xiang pigs had the thinnest backfat.The aver-age backfat thickness of all local pig breeds,except for Congjiang Xiang pig,was significantly higher than that of Yorkshire pigs(P＜0.05).In terms of liver lipid metabolism,the levels of T-CHO,TG and LDL-C in the livers of local Guizhou pigs were higher than those of the Yorkshire pigs(P＜0.05),while high-density lipoprotein cholesterol(HDL-C)levels were significantly lower(P＜0.05).Signifiant differences were observed in the liver lipid indicators of Jiangkou Luobo pigs,Congjiang Xiang pigs,and Qianbei Black pigs compared to Yorkshire pigs(P＜0.05).Additionally,the transcriptional levels of acetyl-CoA carboxylase α(ACACA),sterol regulator element binding protein 1(SREBP-1)and fatty acid synthase(FAS)in livers of local pigs were higher than those of Yorkshire pigs.Particularly,the mRNA expression levels of AC AC A,SREBP-1 and FAS in the livers of Nuogu pigs,Baixi Pigs and Congjiang Xiang Pigs were significantly higher than those in Yorkshire pigs(P＜0.05).Differences in the levels of lipid metabo-lism indexes and mRNA expression levels of lipid synthesis genes in the livers of local pig and Yorkshire pigs in Guizhou indicate that the livers of local pigs have a greater capacity for fatty acid synthesis and fat deposition than those of Yorkshire pigs.These findings not only enhance our understanding of lipid metab-olism regulation in local pigs,but also establish a theoretical foundation for the genetic enhancement of lo-cal pigs breeds and the improvement of meat quality,which is crucial for the conservation and utilization of local pig germplasm resources.关键词
地方猪/肝脏/脂质代谢/脂肪沉积/肉质Key words
local pigs/liver/lipid metabolism/fat deposition/meat quality分类
畜牧业引用本文复制引用
石庆武,张才在,王杰,丁义杰,张依裕,苟昌勇,陈滇黔,敖政..贵州地方猪肝脏脂质代谢及相关基因表达模式分析[J].家畜生态学报,2025,46(10):22-27,6.基金项目
贵州省种业发展项目(黔农计财[2022]10号) （黔农计财[2022]10号）
贵州省科技人才项目(黔科合平台人才[2021]5630号) （黔科合平台人才[2021]5630号）
促进与加拿大、澳大利亚、新西兰及拉美地区科研合作与高层次人才培养项目(留金美[2021]109号) （留金美[2021]109号）
贵州省科技计划项目(黔科合成果[2023]一般133) （黔科合成果[2023]一般133）
铜仁市科技计划项目(铜市科研[2023]54号) （铜市科研[2023]54号）
