解放军医学院学报2025，Vol.46Issue(6)：546-553,8.DOI:10.12435/j.issn.2095-5227.25011403
自助式认知评估测验对老年轻度认知功能障碍诊断效能的初步研究
A preliminary study on diagnostic performance of self-help cognitive assessment test for mild cognitive impairment in the elderly
摘要
Abstract
Background The aging population in China faces a critical challenge due to the high risk of progression from mild cognitive impairment(MCI)to dementia.Existing MCI screening methods are limited by high costs or reliance on specialized professionals,hindering large-scale implementation.Objective To investigate the diagnostic efficacy of the self-help cognitive assessment test(SCAT)for MCI screening in older adults and provide a practical tool for early identification in large-scale settings.Methods The study recruited cognitively normal and MCI elderly individuals aged 60-80 years from a tertiary hospital and communities in Beijing from March to October in 2024.All participants were clinically diagnosed by neurologists using standardized criteria.SCAT,the Montreal Cognitive Assessment Beijing version(MoCA-BJ)were administered.Receiver operating characteristic(ROC)curve analysis was performed to evaluate SCAT's diagnostic performance(sensitivity,specificity).Correlations between SCAT and MoCA-BJ were assessed.Results A total of 205 cognitively normal elderly individuals and 65 elderly individuals with MCI were included in this study.Compared with the MCI group,the cognitively normal group had a higher proportion of individuals with high-level education and a lower proportion of those with junior high school education(χ²=29.224,P＜0.001).There were no significant differences in other general data between the two groups(P＞0.05).The SCAT total score in the MCI group was(37.89±7.81),which was significantly lower than that in the cognitively normal group(50.01±10.00)(P＜0.001,Cohen's d=1.269).The optimal cutoff score of SCAT for screening MCI from the elderly individuals with normal cognitive function was 43 points.At this cutoff,the area under the ROC curve(AUC)was 0.833(95%CI:0.776-0.891),with a sensitivity of 0.780 and specificity of 0.757 for diagnosing MCI.SCAT total scores showed moderate correlations with MoCA-BJ(r=0.482,P＜0.001).Conclusion SCAT demonstrates acceptable diagnostic efficacy in MCI screening for MCI among older adults,with additional advantages of self-administration and mobile application convenience,making it suitable for large-scale screening initiatives.关键词
自助式认知评估测验/轻度认知功能障碍/老年人/量表评价Key words
self-help cognitive assessment test/mild cognitive impairment/the elderly/scale evaluation分类
医药卫生引用本文复制引用
胡瑞康,谭淑平,姜荣环,郭虹,郭晓杰,胡茜,贾娜•木海,张宸赫,王梦雨,董彦彬,范宏振..自助式认知评估测验对老年轻度认知功能障碍诊断效能的初步研究[J].解放军医学院学报,2025,46(6):546-553,8.基金项目
省部级课题(2022YB12) （2022YB12）
