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猪去氧胆酸在糖脂代谢相关疾病中的研究进展

郭文艳 白娟霞 毛华博 刘菊香

兰州大学学报(医学版)2025,Vol.51Issue(9):82-87,6.
兰州大学学报(医学版)2025,Vol.51Issue(9):82-87,6.DOI:10.13885/j.issn.2097-681X.2025.09.011

猪去氧胆酸在糖脂代谢相关疾病中的研究进展

Progress in research on hyodeoxycholic acid in glycolipid metabolism related diseases

郭文艳 1白娟霞 1毛华博 1刘菊香2

作者信息

  • 1. 甘肃中医药大学 第一临床医学院,甘肃 兰州 730000
  • 2. 甘肃省人民医院 内分泌科,甘肃 兰州 730000
  • 折叠

摘要

Abstract

The occurrence of glycolipid metabolism related diseases,such as type 2 diabetes mellitus,non-al-coholic fatty liver disease,atherosclerosis,and dyslipidemia,is intricately linked to disorders in glucose and lipid metabolism.Hyodeoxycholic acid as an important secondary bile acid,that plays a crucial role in regulat-ing lipid metabolism and shows the potential to become a novel therapeutic target for glycolipid metabolic dis-eases.This article gave an review of the mechanism and research progress between hyodeoxycholic acid and glycolipid metabolism related diseases,and explore its potential clinical application value.

关键词

猪去氧胆酸/2型糖尿病/非酒精性脂肪性肝病/动脉粥样硬化/血脂异常

Key words

hyodeoxycholic acid/diabetes mellitus type 2/non-alcoholic fatty liver disease/atherosclerosis/dyslipidemia

分类

临床医学

引用本文复制引用

郭文艳,白娟霞,毛华博,刘菊香..猪去氧胆酸在糖脂代谢相关疾病中的研究进展[J].兰州大学学报(医学版),2025,51(9):82-87,6.

基金项目

国家自然科学基金资助项目(81960160) (81960160)

甘肃省自然科学基金资助项目(24JRRA1060) (24JRRA1060)

兰州大学学报(医学版)

2097-681X

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