环境与职业医学2025，Vol.42Issue(8)：987-993,7.DOI:10.11836/JEOM24504
日常生活来源的环境内分泌干扰物与妊娠期糖尿病关联的研究进展
Research progress on relationship between endocrine disrupting chemicals from daily life and gestational diabetes mellitus
摘要
Abstract
The incidence of gestational diabetes mellitus(GDM)is gradually increasing and has become a significant public health issue.Endocrine disrupting chemicals(EDCs)are a ubiquitous class of exogenous chemical substances that can interfere with hormone synthesis,metabolism,and ac-tivity,and subsequently affect endocrine homeostasis.Humans are extensively and continuously exposed to various EDCs originating from food packaging,plastic products,textiles,electronic goods,as well as cleaning agents and cosmetics in daily life,leading to endocrine and metabolic disorders,such as obesity,insulin resistance,impaired glucose tolerance,and diabetes.Previous studies indicated a close association between EDCs exposure and the occurrence of GDM.This review summarized the correlation between daily life exposure to EDCs and GDM,along with their potential biological mechanisms,including bisphenols,phthalates,per-and polyfluoroalkyl substances,organophosphate esters,parabens,and triclosan,aiming to provide scientific evidence for supporting the effective implementation of public health intervention measures to alleviate and prevent GDM.关键词
环境内分泌干扰物/妊娠期糖尿病/生物学机制Key words
endocrine disrupting chemical/gestational diabetes mellitus/biological mechanism分类
预防医学引用本文复制引用
王乐,朱贝贝,陶芳标..日常生活来源的环境内分泌干扰物与妊娠期糖尿病关联的研究进展[J].环境与职业医学,2025,42(8):987-993,7.基金项目
国家自然科学基金项目(82073564) （82073564）
高校优秀青年人才支持计划重点项目(gxyqZD2021101) （gxyqZD2021101）
安徽省重点研究与开发计划项目(202104j07020034) （202104j07020034）
