皮肤性病诊疗学杂志2025，Vol.32Issue(10)：703-708,6.DOI:10.3969/j.issn.1674-8468.2025.10.002
308nm准分子激光联合火针治疗白癜风的临床效果
Clinical effects of 308 nm excimer laser combined with fire needle in the treatment of vitiligo
摘要
Abstract
Objective To observe the clinical efficacy of 308 nm excimer laser combined with fire needle therapy in the treatment of vitiligo patients.Methods A total of 69 vitiligo patients were enrolled from the 903 Hospital and randomly divided into a control group(34 cases)and an experimental group(35 cases),using a random number table.The control group received 308 nm excimer laser therapy alone,while the experimental group received a combined treatment with 308 nm excimer laser and fire needle therapy.The vitiligo lesion area,clinical efficacy,and incidence of adverse reactions were compared between the two groups.Furthermore,the relationship between the lesion recovery area and patient age was analyzed in both groups.Results Before the treat-ments at the 8 th and 12 th weeks,as well as at the end of the treatment,the vitiligo lesion area in the experimental group(13.77±2.86,12.24±1.86,and 11.33±1.98,respectively)was sig-nificantly smaller than that in the control group(15.83±3.17,13.95±2.23,and 13.25±2.05,respectively)(all P＜0.01).The overall effective rate was significantly higher in the ex-perimental group than in the control group(94.29％vs.73.53％;x2=5.55,P=0.019).However,the total incidence of adverse reactions did not differ significantly between the two groups(P＞0.05).The recovery area of skin lesions in both groups correlated negatively with age(control group:r=-0.32,P=0.043;experimental group:r=-0.21,P=0.023),with the experimental group showing a smaller slope.Conclusions The clinical effectiveness of 308 nm excimer laser combined with fire needle treatment is remarkable,with a reduction in lesion area,faster repigmentation,suitability for a broad age range,safety and reliability.关键词
白癜风/308nm准分子激光/火针/联合治疗Key words
vitiligo/308 nm excimer laser/fire needle/combined treatment引用本文复制引用
宋文韬,黎平,赵玲,陆洁..308nm准分子激光联合火针治疗白癜风的临床效果[J].皮肤性病诊疗学杂志,2025,32(10):703-708,6.基金项目
九〇三医院院内科研项目(KY2022-04) （KY2022-04）
