皮肤性病诊疗学杂志2025，Vol.32Issue(10)：741-745,5.DOI:10.3969/j.issn.1674-8468.2025.10.008
反应性穿通性胶原病典型皮肤镜表现1例
A case of acquired reactive perforating collagen disease with typical dermoscopic features
摘要
Abstract
We report a case of acquired reactive perforating collagen disease with typical der-moscopic features.A 66-year-old woman presented with a 2-year history of generalized erythemas,papules,and itching,which had been aggravated for more than 2 months.Physical examination revealed a large erythema on the back,multiple keratinizing papules with central umbilical fovea in tan color.Erythemas,papules,scratches,and erosions were present on both lower extremities.A surgical scar about 10 cm long was visible on the right abdomen.(Back)Histopathology showed acanthosis,cup-like depression of the epidermis filled with parakeratotic debris,and necrotic col-lagen fibers penetrating the epidermis.Dermatoscopic examination revealed a central yellowish-brown amorphous area with a peripheral white halo,surrounded by pink amorphous area,along with reticular and linear blood vessels.Acquired reactive perforating collagenosis was diagnosed.After one-week treatments with oral Tripterygium wilfordii tablets,Olopatadine tablets,Levocetiri-zine tablets,and Pregabalin capsules,along with topical compounded Miconazole ointment and Polymyxin ointment,and phototherapy,rashes and erosions had basically healed and scabbed o-ver,with significant improvement in itching.After three weeks,a phone follow-up indicated par-tial resolution of the rashes,with itching mostly under control.关键词
反应性穿通性胶原病/皮肤镜Key words
reactive perforating collagen disease/dermatoscope引用本文复制引用
吉娟,徐浩翔,宋昊,许昌春..反应性穿通性胶原病典型皮肤镜表现1例[J].皮肤性病诊疗学杂志,2025,32(10):741-745,5.基金项目
江苏省老年健康科研项目(LKM2022029) （LKM2022029）
江苏省中医药管理局面上项目(MS2022152) （MS2022152）
