皮肤性病诊疗学杂志2025，Vol.32Issue(10)：751-758,8.DOI:10.3969/j.issn.1674-8468.2025.10.010
红皮病型银屑病的研究进展
Research progress on erythrodermic psoriasis
摘要
Abstract
Erythrodermic psoriasis is a rare and unique type of psoriasis that often occurs in in-dividuals with a history of psoriasis.It can affect people of any age but is more common among middle-aged and elderly individuals.The incidence of erythrodermic psoriasis is relatively low worldwide.However,the specific incidence rate varies due to factors such as region and race.This review summarizes its epidemiology,pathogenesis(such as the activation of the Th17/IL-23 axis,and HLA-C*01:02 gene polymorphism),clinical diagnosis(such as biomarkers,IL-17A and CCL20),and treatment advancements(traditional drugs like methotrexate and new biological agents such as IL-17 inhibitors)related to EP.It also explores objective assessment methods for the severity of EP(such as PASI and DLQI scores)and future research directions(such as gene therapy).关键词
红皮病型银屑病/自身免疫性疾病/生物制剂Key words
erythrodermic psoriasis/autoimmune diseases/biological agents引用本文复制引用
杨莹莹,钟远秋,刘芳华,刘守刚,陈永锋..红皮病型银屑病的研究进展[J].皮肤性病诊疗学杂志,2025,32(10):751-758,8.基金项目
广东省医学科学技术研究基金(B2025160) （B2025160）
南方医科大学2024学年国际教育类教学改革研究与实践专项课题(2024GJG032) （2024GJG032）
南方医科大学皮肤病医院住培教育教学改革课题(ZP202403) （ZP202403）
