岭南现代临床外科2025，Vol.25Issue(5)：330-336,7.DOI:10.3969/j.issn.1009-976X.2025.05.008
乳腺癌癌性伤口患者病耻感现状及影响因素预测模型构建
Analysis of factors affecting stigma in patients with breast cancer wounds and construction of a prediction model
摘要
Abstract
Objective To explore the factors influencing stigmatization in patients with malignant breast cancer wounds,identify its core predictive factors,and construct and validate a clinical predictive model for stigmatization.Methods A cross-sectional survey was conducted on 67 patients using the following instruments:general information questionnaire,Stigma Scale for Chronic Illnesses 8-item version(SSCI-8),Toronto Wound Symptom Assessment System-Wounds(TSAS-W),Self-Rating Anxiety Scale(SAS),Self-Rating Depression Scale(SDS),Social Support Rating Scale(SSRS),and Quality of Life Instruments for Cancer Patients-Breast Cancer(QLICP-BR).Data analysis was performed using univari-ate analysis,Pearson correlation,and multiple linear regression analysis.Results The overall score for stigmatization was 13.3±5.76 points.Correlation analysis showed that stigmatization was significantly positively correlated with anxiety(r=0.537)and depression(r=0.464),and wound symptoms(r=0.389)(all P<0.05),strongly negatively correlated with quality of life(r=-0.718,P<0.01),and marginally significantly negatively correlated with social support(r=-0.229,P=0.062).Multivariate linear regression analysis showed that:Quality of life(β=-0.666,P<0.01)was the strongest negative predictor of stigma,while anxiety(β=0.234,P=0.088)and depression(β=-0.251,P=0.095)had marginal predictive effects.The final model explained 51.5%of the variance in stigmatization(adjusted R3=0.515,F=15.003,P<0.01).Conclusion Stigmatization in patients with breast cancer wounds has a significant statistical association with quality of life,and a marginally significant association with anxiety and depression levels.Wound management can be combined with a focus on enhancing patient quality of life and alleviating anxiety and depression,in order to reduce patients′ level of stigmatization.关键词
乳腺癌性伤口/病耻感/影响因素/预测模型Key words
breast cancer wounds/stigma/influencing factors/predictive mode分类
临床医学引用本文复制引用
林爱怡,王秀,李玲,邱良枝,吴仙蓉..乳腺癌癌性伤口患者病耻感现状及影响因素预测模型构建[J].岭南现代临床外科,2025,25(5):330-336,7.基金项目
广东省医学科学技术研究基金项目(A2022294) （A2022294）
