杨思邈 1王建芳 1王志斌 1李薇 2黄亚芳 1蒋婉婷 1庞家乐 1陈润花1
作者信息
- 1. 北京中医药大学东方医院脾胃肝胆科,北京 100078
- 2. 北京中医药大学东方医院肛肠科,北京 100078
- 折叠
摘要
Abstract
Objective To evaluate the efficacy and safety of combined acupuncture and traditional Chinese medicine(TCM)in treating slow transit constipation.Methods Randomized controlled trials on combined acupuncture and TCM for slow transit constipation were searched in databases including CNKI,VIP,Wanfang,CBM,PubMed,Web of Science,and Cochrane Library,with the search period spanning from database inception to May 1,2025.Meta-analysis of efficacy rates and adverse drug reactions was performed using RevMan 5.4 and Stata 17 software.Results Twenty-two RCTs involving 2473 patients were included after screening based on inclusion and exclusion criteria.Meta-analysis results demonstrated that the experimental group significantly outperformed the control group in the following aspects:total efficacy rate[RR=1.32,95%CI(1.27,1.37),P<0.00001],stool consistency[WMD=0.57,95%CI(0.38,0.76),P<0.00001],degree of straining during defecation[WMD=0.63,95%CI(0.47,0.80),P<0.00001],defecation time[WMD=0.58,95%CI(0.39,0.77),P<0.00001],defecation frequency[WMD=0.66,95%CI(0.39,0.92),P<0.0001],total TCM symptom score[WMD=3.26,95%CI(2.08,4.44),P<0.0001],colonic transit test[WMD=6.15,95%CI(4.25,8.04),P<0.00001],incidence of adverse reactions[RR=0.25,95%CI(0.10,0.64),P<0.01].Conclusion Combined acupuncture and TCM is effective and safe for slow transit constipation.关键词
疗效/Meta分析/慢传输型便秘/针药并用Key words
Efficacy/Meta-analysis/Slow transit constipation/Combined acupuncture and traditional Chinese medicine分类
中医学
