神经病学与神经康复学杂志2025,Vol.21Issue(5):361-367,7.DOI:10.12022/jnnr.2025-0203
中西医结合治疗发作性睡病的研究与展望
Research and prospects of integrated traditional Chinese and western medicine in the treatment of narcolepsy
摘要
Abstract
Narcolepsy(NC)is a rare chronic neurological disorder.Current western medical treatments(such as central stimulants,antidepressants,and sodium gamma-hydroxybutyrate)primarily aim to reduce excessive daytime sleepiness,control cataplexy,and improve nighttime sleep,thereby alleviating clinical symptoms.However,long-term use of western medications may lead to issues such as drug dependence,drug resistance,and adverse effects.In contrast,traditional Chinese medicine(TCM),guided by the principles of"treatment based on syndrome differentiation"and"holistic regulation",offers unique advantages in improving NC symptoms,reducing the risk of disease recurrence,and enhancing quality of life.It can compensate for the limitations of western medicine,reduce dosage requirements of western drugs,and mitigate their side effects,thereby improving treatment safety.Additionally,TCM may delay cognitive impairment and protect brain function.Therefore,this study systematically reviews recent advances in both western medicine and TCM for the treatment of NC,and further explores the benefits of integrated western and TCM approaches under a holistic medical model,with the aim of optimizing clinical strategies and providing new insights for the management of NC.关键词
发作性睡病/中医药/中西医结合/优势/治疗进展Key words
Narcolepsy/Traditional Chinese medicine/Integrated traditional Chinese and western medicine/Advantages/Treatment progress引用本文复制引用
张梦雪,张娟,李净娅,张伟骏,郑国庆..中西医结合治疗发作性睡病的研究与展望[J].神经病学与神经康复学杂志,2025,21(5):361-367,7.基金项目
浙江省中医药重点学科建设项目中医脑病学(2024-XK-28) (2024-XK-28)
浙江省中医院优势学科神经病学(浙中医字[2022]34号) Zhejiang Provincial Key Discipline Construction Project in Traditional Chinese Medicine:Traditional Chinese Medicine Neurology(2024-XK-28) (浙中医字[2022]34号)
Zhejiang Provincial Hospital of Chinese Medicine Advantageous Discipline:Neurology(Zhejiang Provincial Hospital of Chinese Medicine Document[2022]No.34) (Zhejiang Provincial Hospital of Chinese Medicine Document[2022]No.34)