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Engineered RNA-based activation system for coronavirus sensing in live cells

Leiping Zeng Christian Otero Lei S.Qi

生物设计研究（英文）2025，Vol.7Issue(3)：14-24,11.

生物设计研究（英文）2025，Vol.7Issue(3)：14-24,11.DOI:10.1016/j.bidere.2025.100040

Engineered RNA-based activation system for coronavirus sensing in live cells

Leiping Zeng ¹Christian Otero ²Lei S.Qi³

作者信息

1. Department of Bioengineering,Stanford University,Stanford,CA,94305,USA
2. Department of Chemical Engineering,Stanford University,Stanford,CA,94305,USA||Sarafan ChEM-H,Stanford University,Stanford,CA,94305,USA
3. Department of Bioengineering,Stanford University,Stanford,CA,94305,USA||Sarafan ChEM-H,Stanford University,Stanford,CA,94305,USA||Chan Zuckerberg Biohub-San Francisco,San Francisco,CA,94158,USA
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摘要

关键词

RNA sensor/Coronavirus/Live cell detection/Antiviral/Synthetic biology

Key words

RNA sensor/Coronavirus/Live cell detection/Antiviral/Synthetic biology

引用本文复制引用

Leiping Zeng,Christian Otero,Lei S.Qi..Engineered RNA-based activation system for coronavirus sensing in live cells[J].生物设计研究（英文）,2025,7(3):14-24,11.

基金项目

The authors thank all members of the Lei Stanley Qi lab for facili-tating experiments and useful discussions.The project was supported by a contract grant from Bill & Melinda Gates Foundation(INV-035661)and in part by funding to L.S.Q.as a Chan Zuckerberg Biohub-San Francisco Investigator.C.O.is supported by the National Science Foundation Graduate Research Fellowship Program(Grant DGE-2146755)and the Sarafan ChEM-H Chemistry-Biological Interface Training Program.L.S.Q.is a Chan Zuckerberg Biohub-San Francisco Investigator. （INV-035661）

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