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人脐带间充质干细胞在皮肤创面修复中的研究进展

刘昕雨 孔萌萌 付乙 赖家林 李峻 孙江华

实用医学杂志2025,Vol.41Issue(21):3462-3466,5.
实用医学杂志2025,Vol.41Issue(21):3462-3466,5.DOI:10.3969/j.issn.1006-5725.2025.21.024

人脐带间充质干细胞在皮肤创面修复中的研究进展

The role of human umbilical cord mesenchymal stem cells in skin wound repair:A literature review

刘昕雨 1孔萌萌 1付乙 1赖家林 1李峻 1孙江华2

作者信息

  • 1. 湖北工业大学生命科学与健康工程学院(湖北 武汉 430068)
  • 2. 武警湖北省总队医院门诊部(湖北 武汉 430642)
  • 折叠

摘要

Abstract

Mesenchymal stem cells(MSCs)are multipotent stromal cells that possess the capacity for self-renewal and differentiation into multiple cell lineages.Due to the ease of procurement,robust expansion in vitro,the multipotency,they are recognized as a vital source of stem cells in the field of regenerative medicine.MSCs can be isolated from various tissues,including bone marrow,adipose tissue,and umbilical cord.Research indicates that Human umbilical cord mesenchymal stem cells(hUCMSCs)play an effective role in wound healing and tissue regeneration,and can be utilized for the repair of skin wounds.They are also considered to be the most promising seed cells for skin tissue engineering.This review aims to provide an overview of the biological characteristics of hUCMSCs,the mechanisms in promoting skin wound healing,and their clinical applications.

关键词

脐带间充质干细胞/皮肤/创面修复

Key words

human umbilical cord mesenchymal stem cells/skin/wound repair

分类

临床医学

引用本文复制引用

刘昕雨,孔萌萌,付乙,赖家林,李峻,孙江华..人脐带间充质干细胞在皮肤创面修复中的研究进展[J].实用医学杂志,2025,41(21):3462-3466,5.

基金项目

湖北省卫生健康委科研项目(面上项目)(编号:WJ2023M093) (面上项目)

实用医学杂志

OA北大核心

1006-5725

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