无机材料学报2025，Vol.40Issue(10)：1129-1136,8.DOI:10.15541/jim20240530
负载硫化铋纳米簇的硅基杂化胶束的制备及其光热抗菌性能
Bismuth Sulfide Nanoclusters-loaded Silica-based Hybrid Micelles:Preparation and Photothermal Antibacterial Property
摘要
Abstract
As a new type of photothermal compound,bismuth-based nanomaterials have advantages of low toxicity,environmental friendliness,and cheap raw materials,showing great application potential in biological photothermal therapy,but their photothermal conversion efficiency and antibacterial property are still low.In this study,based on the confined gelation method reported by previous literature,a silica-based hybrid micellar precursor with organosilica-stabilized micellar cores was prepared using Pluronic polymer F127 and 3-mercaptopropyl-trimethoxy-silane as raw materials,and a facile"confined reduction/sulfuration"method was further developed,that is,the abundant thiol groups in the organosilica framework of the micelle core were used as restricted adsorption sites,sodium borohydride was used as reducing agent,and sodium sulfide was used as vulcanizing agent to prepare ultra-small and amorphous bismuth sulfide clusters-supported silica-based hybrid micellar system.The results show that the functional hybrid micellar system has excellent photothermal performance,and its photothermal conversion efficiency is up to 86.93％,which may be attributed to monodisperse and stable loading of bismuth sulfide clusters with defective structure in the organosilica framework of hybrid micellar system,which enhances light absorption capacity of bismuth sulfide nanomaterials in the near-infrared wavelength range.The in vitro antimicrobial experiments show that this bismuth-containing system exhibits excellent photothermal antibacterial properties under irradiation of 808 nm near-infrared laser and good biocompatibility.关键词
氧化硅/嵌段共聚物/硫化铋/光热性能/抗菌剂Key words
silicon oxide/block copolymer/bismuth sulfide/photothermal property/antibacterial agent分类
化学工程引用本文复制引用
赵丽华,王言帅,尹昕妩,毛叶琼,牛德超..负载硫化铋纳米簇的硅基杂化胶束的制备及其光热抗菌性能[J].无机材料学报,2025,40(10):1129-1136,8.基金项目
国家自然科学基金(32371406) （32371406）
上海市优秀学术/技术带头人项目(22XD1421100)National Natural Science Foundation of China(32371406) （22XD1421100）
Program of Shanghai Academic/Technology Research Leader(22XD1421100) （22XD1421100）
