畜牧兽医学报2025,Vol.56Issue(10):4774-4786,13.DOI:10.11843/j.issn.0366-6964.2025.10.002
N6-甲基腺苷(m6A)修饰在畜禽遗传育种与繁殖中的调控作用研究进展
Research Progress of N6-methyladenosine(m6A)Modification in Regulation of Livestock and Poultry Genetic Breeding and Reproduction
摘要
Abstract
N6-methyladenosine(m6A)modification is a widespread RNA modification in eukary-otic cells and an important component of RNA epigenetic modification.m6A modification mainly regulates the transcription,processing,and degradation of mRNA and non-coding RNA(ncRNA),thus regulating a variety of physiological and metabolic activities.In livestock and poultry,m6A modification is involved in a variety of molecular mechanisms of life activities,such as muscle development,lipid metabolism,and reproduction.In this review,the regulatory role of m6A modification in livestock and poultry genetic breeding and reproduction is summarized.In addition,the application and future direction of m6A modification in livestock and poultry are also discussed.关键词
m6A修饰/畜禽/遗传育种与繁殖/生长发育/调控Key words
m6A modification/livestock and poultry/genetic breeding and reproduction/growth and development/regulation分类
农业科技引用本文复制引用
邵嘉皓,张艳婕,赵永聚..N6-甲基腺苷(m6A)修饰在畜禽遗传育种与繁殖中的调控作用研究进展[J].畜牧兽医学报,2025,56(10):4774-4786,13.基金项目
国家自然科学基金面上项目(32372834) (32372834)
重庆市现代农业产业技术体系资助(草食牲畜:CQMAITS202513) (草食牲畜:CQMAITS202513)