临床医学工程2025，Vol.32Issue(10)：1049-1053,5.DOI:10.3969/j.issn.1674-4659.2025.10.1049
针刺联合重复经颅磁刺激对慢性失眠患者睡眠结构的影响
Impact of Acupuncture Combined with Repetitive Transcranial Magnetic Stimulation on Sleep Structure in Patients with Chronic Insomnia
摘要
Abstract
Objective To observe the impact of acupuncture combined with repeated transcranial magnetic stimulation(rTMS)on sleep structure in patients with chronic insomnia.Methods 92 patients with chronic insomnia admitted to our hospital from October 2024 to April 2025 were selected and randomly divided into combined group and control group.The control group was treated with rTMS,while the combined group was treated with acupuncture on the basis of the control group.Both groups were treated for 4 weeks.The Micro-motion Sensitive Mattress Monitoring System indicators[monitor the total sleep time(TST),sleep latency(SL),number of awakenings(NA),wake after sleep onset(WASO),percentage of non rapid eye movement sleep stages 1 and 2(N1+N2)%,and percentage of non rapid eye movement sleep stage 3(N3%)]and the Pittsburgh Sleep Quality Index(PSQI)socre before and after treatment,and clinical efficacy were compared between the two groups.Results After 4 weeks of treatment,the TST of the two groups was prolonged compared with that before treatment,N3%was higher than that before treatment,SL and WASO were shorter than those before treatment,NA was less than that before treatment,and(N1+N2)%was lower than that before treatment;while the TST of the combined group was longer than that of the control group,SL and WASO were shorter than those of the control group,NA was less than that of the control group,no significant difference was found in the(N1+N2)%and N3%between the two groups(P>0.05).After 4 weeks of treatment,the PSQI scores of the two groups were lower than those before treatment,and the PSQI score of the combined group was lower than that of the control group(P<0.05).The total effective rate of the treatment in the combined group was 97.83%,significantly higher than 82.61%in the control group(P<0.05).Conclusions Acupuncture combined with rTMS can significantly improve the subjective sleep quality and objective sleep structure of patients with chronic insomnia,and the overall clinical efficacy is significantly higher than that of rTMS treatment alone.The mechanism may be attributed to the synergistic effect of"neural regulation+visceral regulation".关键词
针刺/重复经颅磁刺激/慢性失眠/睡眠结构/微动敏感床垫式监测系统Key words
Acupuncture/Repetitive transcranial magnetic stimulation/Chronic insomnia/Sleep structure/Micro-motion sensitive mattress monitoring system分类
医药卫生引用本文复制引用
王维维,王政研,陈婷,唐源,皮燕,黄湘玉..针刺联合重复经颅磁刺激对慢性失眠患者睡眠结构的影响[J].临床医学工程,2025,32(10):1049-1053,5.基金项目
国家自然科学基金青年项目(项目编号:81503670) （项目编号:81503670）
四川省中医药管理局中医药科研专项课题(项目编号:2024MS242) （项目编号:2024MS242）
