摘要
Abstract
Objective To analyze the expression of white blood cell count(WBC),high-sensitivity C-reactive protein(hs-CRP),serum amyloid A(SAA)and neutrophil-to-lymphocyte ratio(NLR)in patients with stable chronic obstructive pulmonary disease(SCOPD)and acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods A total of 72 patients with COPD admitted to Yanshan County Hospital of Traditional Chinese Medicine from May 2022 to May 2024 were selected.Among them,21 patients with SCOPD were set as SCOPD group,and 51 patients with AECOPD were set as AECOPD group.The WBC,hs-CRP,SAA and NLR indexes were detected.The results of WBC,hs-CRP,SAA and NLR were compared between the two groups.The ROC curve was drawn to analyze the diagnostic value of WBC,hs-CRP,SAA and NLR indexes for AECOPD.Results The levels of WBC,hs-CRP,SAA and NLR in AECOPD group were higher than those in SCOPD group(P＜0.05).ROC curve analysis showed that WBC,hs-CRP,SAA and NLR had definite diagnostic value for AECOPD(P＜0.05),and the AUC value of combined detection of WBC,hs-CRP,SAA and NLR was greater than that of single detection(P＜0.05).Conclusion WBC,hs-CRP,SAA and NLR are abnormally highly expressed in AECOPD patients,and their levels are higher than those in SCOPD patients.Meanwhile,those indexes have a definite diagnostic effect in AECOPD detection,and the combined detection has better diagnostic efficacy.关键词
慢性阻塞性肺疾病/慢性阻塞性肺疾病稳定期/慢性阻塞性肺疾病急性加重期/白细胞计数/高敏C反应蛋白/血清淀粉样蛋白A/中性粒细胞/淋巴细胞比值/诊断效能分类
医药卫生
