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经颅微电流刺激联合音乐干预对失眠及其认知改善的临床研究

张慧飞 娄妤堃 董贞 张永祥 刘浩然 周超前 何清华 孙志远 吕玉丹

中风与神经疾病杂志2025,Vol.42Issue(10):904-910,7.
中风与神经疾病杂志2025,Vol.42Issue(10):904-910,7.DOI:10.19845/j.cnki.zfysjjbzz.2025.0167

经颅微电流刺激联合音乐干预对失眠及其认知改善的临床研究

Effect of cranial electrotherapy stimulation combined with music intervention in improving insomnia and cognitio n:A clinical study

张慧飞 1娄妤堃 2董贞 1张永祥 1刘浩然 2周超前 2何清华 3孙志远 4吕玉丹1

作者信息

  • 1. 吉林大学白求恩第一医院神经内科,吉林 长春 130021
  • 2. 浙江脑科技有限公司,浙江 杭州 310000
  • 3. 香港中文大学,广东 深圳 518000
  • 4. 中国科学院长春光学精密机械与物理研究所,吉林 长春 130031
  • 折叠

摘要

Abstract

Objective To investigate the clinical effect of cranial electrotherapy stimulation(CES)combined with music intervention on insomnia and its effect in improving cognitive function.Methods A total of 75 patients with insom-nia were randomly divided into control group with treatment-as-usual(TAU)alone,CES+double beat+TAU group,and CES+pink noise+TAU group,with a sample size of 1∶1∶1 for the three groups.Sleep onset latency(SL),total sleep time(TST),and sleep quality were analyzed before and after treatment,and the Go/NoGo paradigm for the assessment of cogni-tive function was used to assess the effect of CES combined with music intervention in improving cognitive function.Results As for the treatment of insomnia,the experimental groups had significant changes in sleep quality(PSQI and SRSS)(P<0.05)and a significant reduction in sleep latency(P<0.05)after treatment,with a significantly higher reduc-tion rate than the control group.As for cognitive function,there was a reduction in the latency of Go-N2 and Go-P3 and an increase in amplitude in the patients with insomnia after CES combined with music intervention,as well as reductions in the latency and amplitude of NoGo-N2 and NoGo-P3.Conclusion CES combined with music intervention can safely and effectively shorten sleep latency and improve sleep quality and cognitive function.

关键词

失眠/CES加载音乐/睡眠潜伏期/睡眠质量/认知功能

Key words

Insomnia/Cranial electrotherapy stimulation combined with music intervention/Sleep latency/Sleep quality/Cognitive function

分类

医药卫生

引用本文复制引用

张慧飞,娄妤堃,董贞,张永祥,刘浩然,周超前,何清华,孙志远,吕玉丹..经颅微电流刺激联合音乐干预对失眠及其认知改善的临床研究[J].中风与神经疾病杂志,2025,42(10):904-910,7.

基金项目

科技创新2030脑科学与类脑研究(2202ZD0210500) (2202ZD0210500)

吉林省科技厅自然科学基金项目(YDZJ202201ZYTS543) (YDZJ202201ZYTS543)

中风与神经疾病杂志

1003-2754

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