中国肺癌杂志2025，Vol.28Issue(8)：644-646,3.DOI:10.3779/j.issn.1009-3419.2025.102.31
肺腺癌患者接受免疫检查点抑制剂治疗后引发巨细胞病毒胃炎1例病例报道
Cytomegalovirus Gastritis Induced by Immune Checkpoint Inhibitors Treatment in Lung Adenocarcinoma:A Case Report
摘要
Abstract
Immune checkpoint inhibitors(ICIs)have been approved for the treatment of a variety of solid tumors and hematological malignancies.Adverse reactions caused by ICIs have been gradually focused on.Cytomegalovirus(CMV)gastritis after ICIs treatment is relatively rare.Here we reported a case of advanced lung adenocarcinoma who experienced re-current upper abdominal pain and vomiting after Pembrolizumab treatment.CMV gastritis was diagnosed through gastroscopy.The patient's symptoms improved after antiviral treatment.During the treatment of ICIs,attention should be paid to the differ-ential diagnosis of upper abdominal pain symptoms,and vigilance should be maintained against CMV gastritis.It is difficult to differentiate CMV gastritis and immune-related gastritis judging from symptoms,and gastroscopy is important for differential diagnosis.关键词
肺肿瘤/免疫检查点抑制剂/巨细胞病毒胃炎/病例报道Key words
Lung neoplasms/Immune checkpoint inhibitors/Cytomegalovirus gastritis/Case report引用本文复制引用
斯晓燕,谭蓓,程欣,王孟昭,张晓彤,张力..肺腺癌患者接受免疫检查点抑制剂治疗后引发巨细胞病毒胃炎1例病例报道[J].中国肺癌杂志,2025,28(8):644-646,3.基金项目
This paper was supported by the grants from Zhongguancun Precision Medicine Foundation(No.ZLXGBX-KYM-040-01)and Bethune Charitable Foundation Advanced Solid Tumor Research Funding(No.STLKY0056)(Both to Li ZHANG). 本文受中关村精准医学基金会肿瘤血管靶向科研项目(No.ZLXGBXKYM-040-01)和北京白求恩公益基金会晚期实体瘤科研项目(No.STLKY0056)资助 （No.ZLXGBX-KYM-040-01）
