中国防痨杂志2025，Vol.47Issue(11)：1421-1425,5.DOI:10.19982/j.issn.1000-6621.20250218
电子鼻在肺结核快速诊断中的应用
Application of electronic nose in rapid diagnosis of pulmonary tuberculosis
摘要
Abstract
Pulmonary tuberculosis(PTB)remains a major global public health challenge,and timely diagnosis is critical for effective epidemic control and transmission reduction.Conventional diagnostic methods,such as sputum culture,are time-consuming and require specialized laboratory facilities,limiting their accessibility in primary care and resource-limited settings.In recent years,electronic nose(eNose)technology has gained increasing attention as a promising tool for the rapid diagnosis of pulmonary tuberculosis,due to its non-invasiveness,speed,and high sensitivity.Emerging evidence suggests that eNose technology can rapidly identify active pulmonary tuberculosis by analyzing volatile organic compounds(VOCs)in exhaled breath.However,its clinical translation remains limited by several challenges,including the lack of standardized instrumentation,variability in data interpretation,and insufficient integration into routine diagnostic workflows.The author provides a comprehensive overview of the current state of eNose applications in tuberculosis diagnosis,elucidating its underlying mechanisms,diagnostic advantages,and existing barriers,and discusses future directions to improve early case detection and advance innovative diagnostic strategies for tuberculosis control.关键词
电子鼻/结核,肺/诊断技术,呼吸系统Key words
Electronic nose/Tuberculosis,pulmonary/Diagnostic techniques,respiratory system分类
医药卫生引用本文复制引用
王可,孙虎,拜合提尼沙·吐尔地..电子鼻在肺结核快速诊断中的应用[J].中国防痨杂志,2025,47(11):1421-1425,5.基金项目
Science and Technology Supporting Xinjiang Program(Directive Project),Xinjiang Uygur Autonomous Region(2024E02048) （Directive Project）
Open Funded Project of the Key Laboratory of Xinjiang Regional High-incidence Disease Ministry of Education(2024A03) 新疆维吾尔自治区科技支疆计划(指令性)项目(2024E02048) （2024A03）
新疆地区高发疾病研究教育部重点实验室开放课题(2024A03) （2024A03）
