中国防痨杂志2025，Vol.47Issue(11)：1454-1458,5.DOI:10.19982/j.issn.1000-6621.20250131
一起基层养老院结核病聚集性疫情调查分析
Investigation and analysis of a tuberculosis cluster outbreak in a primary elderly care facility
摘要
Abstract
Objective:To analyze the epidemiological characteristics and response measures of a tuberculosis(TB)cluster outbreak in a grassroots nursing home,and summarize the experience in managing TB outbreaks among special populations in key settings,and provide references for TB prevention and control in similar institutions.Methods:On April 15,2021,the disease control agency identified two pulmonary tuberculosis cases in a grassroots nursing home through the China Disease Control and Prevention Information System,prompting immediate on-site epidemiological investigation and outbreak response.The outbreak was monitored for 40 months,during which 11 rounds of screening were performed.The screening included assessments for suspected pulmonary tuberculosis symptoms,Mycobacterium tuberculosis infection testing,chest X-ray examinations,and laboratory tests.Descriptive epidemiological methods were used to analyze case characteristics and intervention processes.Results:Among 324 elderly residents and staff in the nursing home,36 active pulmonary tuberculosis cases were identified,along with 116 latent tuberculosis infection(LTBI)cases.The first screening round after the initial two index cases detected 23 additional pulmonary tuberculosis cases(69.44％,25/36),while 11 more cases were identified during 18 months of follow-up.No further cases were detected after 18 months.Comorbidities were common among residents,and the uptake of preventive chemotherapy was low(51 cases,43.97％).Conclusion:Grassroots nursing homes were places with high incidence of tuberculosis.Active monitoring should be carried out every day in grassroots nursing homes.Epidemiological investigation and epidemic situation disposal should be carried out immediately when pulmonary tuberculosis patients were found.Preventive treatment should be actively carried out for those with LTBI,and follow-up observation time should be extended.关键词
结核,肺/预防和控制/老人养老院/老年人/疾病暴发流行/接触者追踪Key words
Tuberculosis,pulmonary/prevention and control/Homes for the aged/Aged/Cluster outbreak/Contact tracking分类
医药卫生引用本文复制引用
马樱子,代晓琦,张扬,何涛,耿海洋,李仁忠..一起基层养老院结核病聚集性疫情调查分析[J].中国防痨杂志,2025,47(11):1454-1458,5.基金项目
2026年河北省医学科学研究课题计划(20261276) Hebei Medical Science Research Project Plan 2026(20261276) （20261276）
