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首页|期刊导航|中国肛肠病杂志|腹腔镜手术治疗粘连性肠梗阻的疗效及对炎症因子水平及免疫功能指标的影响

腹腔镜手术治疗粘连性肠梗阻的疗效及对炎症因子水平及免疫功能指标的影响

周理 刘颖 张洋洋

中国肛肠病杂志2025,Vol.45Issue(10):17-19,3.
中国肛肠病杂志2025,Vol.45Issue(10):17-19,3.

腹腔镜手术治疗粘连性肠梗阻的疗效及对炎症因子水平及免疫功能指标的影响

Efficacy of Laparoscopic Surgery in Treatment of Adhesive Intestinal Obstruction and Its Influence on Levels of Inflammatory Factors and Immune Function Indicators

周理 1刘颖 2张洋洋1

作者信息

  • 1. 郑州大学附属郑州中心医院胃肠代谢外科(河南 郑州 450000)
  • 2. 河南中医药大学第五临床医学院,郑州人民医院(河南 郑州 450000)
  • 折叠

摘要

Abstract

Objective To observe and analyze the efficacy of laparoscopic surgery in the treatment of patients with adhesive intestinal obstruction and its influence on the levels of inflammatory factors and immune function indicators.Methods A total of 60 patients with adhesive intestinal obstruction admitted to our hos-pital from February 2020 to February 2025 were randomly divided into a control group and an observation group,with 30 cases in each group.Patients in the control group were treated with open surgery,while those in the observation group were treated with laparoscopic surgery.The efficacy,levels of inflammatory factors,immune function indicators and surgery-related indicators of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).Before treat-ment,there was no statistically significant difference in the levels of interleukin-6(IL-6)and C-reactive protein(CRP)between the two groups(P>0.05).After treatment,the levels of IL-6 and CRP in both groups increased,which were lower in the observation group than in the control group(P<0.05).Before treatment,there was no statistically significant difference in the levels of CD3+,CD4+and CD8+between the two groups(P>0.05).After treatment,the levels of CD3+and CD4+in the observation group were higher than those in the control group(P<0.05),and the level of CD8+was lower than that in the control group(P<0.05).The operation time,time to get out of bed,time to resume anal exhaust and length of hospital stay of the observa-tion group were all shorter than those of the control group(P<0.05),and the intraoperative blood loss was less than that of the control group(P<0.05).Conclusion Compared with traditional open surgery,laparo-scopic surgery has a significant effect in the treatment of adhesive intestinal obstruction.It not only has less sur-gical trauma,shorter operation time and less intraoperative blood loss,but also can reduce the body's inflamma-tory response,protect immune function,and effectively promote the postoperative recovery of patients.Laparo-scopic surgery is recommended as the preferred clinical treatment option.

关键词

粘连性肠梗阻/腹腔镜手术/治疗效果/炎症指标/免疫功能

Key words

Adhesive intestinal obstruction/Laparoscopic surgery/Treatment effect/Inflammatory indica-tors/Immune function

引用本文复制引用

周理,刘颖,张洋洋..腹腔镜手术治疗粘连性肠梗阻的疗效及对炎症因子水平及免疫功能指标的影响[J].中国肛肠病杂志,2025,45(10):17-19,3.

中国肛肠病杂志

1000-1174

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