中国康复理论与实践2025，Vol.31Issue(10)：1164-1171,8.DOI:10.3969/j.issn.1006-9771.2025.10.007
阈值吸气肌训练对肺癌术后患者肺康复影响的Meta分析
Effect of threshold inspiratory muscle training on pulmonary rehabilitation in postoperative lung cancer patients:a meta-analysis
摘要
Abstract
Objective To systematically evaluate the effect of threshold inspiratory muscle training on pulmonary rehabilitation in postoperative lung cancer patients,with a focus on exploring the difference in efficacy under different interven-tion modes. Methods Randomized controlled trials on the effect of threshold inspiratory muscle training on pulmonary rehabilitation in postoperative lung cancer patients were retrieved from PubMed,Cochrane Library,Embase,Web of Science,CNKI,Wanfang data,VIP and China Biomedical Literature Database.Meanwhile,gray literature from ProQuest and clinicaltrials.gov was searched as supplements.The retrieval period was from the establishment of each data-base to May 9,2025.Cochrane 5.1.0 was used to evaluate the quality of literature,and a meta-analysis was per-formed using RevMan 5.4. Results Twelve studies involving 701 patients were included,all of which were of moderate to high quality.Threshold inspiratory muscle training could reduce the pulmonary complications of postoperative lung cancer patients(OR=0.45,95%CI 0.29 to 0.68,P<0.001),shorten the hospital stay(MD=-1.85,95%CI-3.29 to-0.42,P=0.010),improve the inspiratory muscle strength(MD=5.84,95%CI 0.96 to 10.71,P=0.020),enhance their ex-ercise endurance(SMD=0.40,95%CI 0.10 to 0.71,P=0.010),and did not increase the risk of pulmonary air leakage(OR=0.88,95%CI 0.47 to 1.63,P=0.680).Subgroup analysis revealed that shortening of hospital stay(MD=-2.98,95%CI-5.87 to-0.09,P=0.040)and the improvement in exercise endurance(SMD=0.57,95%CI 0.14 to 1.00,P=0.009)were significant only when threshold inspiratory muscle training was combined with aerobic exercise.However,standalone threshold inspiratory muscle training showed no statistical signifi-cance in these two outcomes. Conclusion Threshold inspiratory muscle training can effectively reduce postoperative pulmonary complications and im-prove inspiratory muscle strength in postoperative lung cancer patients with good safety.Threshold inspiratory muscle training could shorten hospital stay and improve exercise endurance only when combining with aerobic exercise.关键词
肺癌/阈值吸气肌训练/肺康复/Meta分析Key words
lung cancer/threshold inspiratory muscle training/pulmonary rehabilitation/meta-analysis分类
临床医学引用本文复制引用
赵英楠,郑鑫彤,刘俊玲,王紫丹,吴泓悦,李冰,李燕..阈值吸气肌训练对肺癌术后患者肺康复影响的Meta分析[J].中国康复理论与实践,2025,31(10):1164-1171,8.基金项目
1.天津市医学重点学科(专科)建设项目(No.TJYXZDXK-011A) （专科）
2.天津医科大学医院管理创新研究项目(No.2023YG12) Supported by Construction Project of Tianjin Key Medical Disciplines(Specialties)(No.TJYXZDXK-011A)and Hospital Management Innovation Research Project of Tianjin Medical University(No.2023YG12) （No.2023YG12）
