农学学报2025，Vol.15Issue(10)：53-64,12.
5-氨基乙酰丙酸合成、代谢与应用的研究进展
Biosynthesis,Metabolism and Application of 5-aminolevulinic Acid
摘要
Abstract
5-Aminolevulinic acid(5-ALA)is widely present in animals,plants,and microbial cells and serves as a key precursor for tetrapyrrole compounds.It participates in the synthesis of essential metabolites such as heme,vitamin B12,and chlorophyll,exhibiting diverse physiological functions.This paper summarized the biosynthesis pathway of 5-ALA and its transport mechanism across different cell types,analyzed the functions and regulatory mechanisms of important downstream metabolites derived from 5-ALA,and reviewed the current applications of 5-ALA in pharmaceutical and agricultural fields.Furthermore,this paper highlighted existing challenges,including immaturity of biosynthesis technology and lack of standardized application protocols,and provided future research prospects to guide its potential applications in agriculture.关键词
5-氨基乙酰丙酸/生物合成/转运/代谢物/应用领域Key words
5-aminolevulinic acid/biosynthesis/transport/metabolites/application field分类
农业科技引用本文复制引用
杨玉婷,蔡爽,叶长川,谯仕彦..5-氨基乙酰丙酸合成、代谢与应用的研究进展[J].农学学报,2025,15(10):53-64,12.基金项目
国家重点研发计划项目课题"肠道微生物代谢物和宿主中间代谢物高效制备"(2022YFC2105001) （2022YFC2105001）
北京科技计划课题"生物合成提高畜禽免疫力新型饲料添加剂关键技术研究与产品研发"(Z221100006422006) （Z221100006422006）
家畜产业技术体系北京市创新团队"生猪营养与饲料岗位专家建设"(BAIC05-2025) （BAIC05-2025）
拼多多-中国农业大学研究基金资助"基于合成生物学的饲用微生物工厂研发"(PC2023A01001). （PC2023A01001）
