中国输血杂志2025，Vol.38Issue(10)：1320-1326,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.10.004
通用型红细胞紧急抢救失血性休克患者的临床应用研究
Clinical study on the application of universal red blood cells in emergency treatment for patients with hemorrhagic shock
摘要
Abstract
Objective To evaluate the safety and efficacy of the emergency infusion protocol for universal red blood cells by analyzing its clinical application in patients treated at our hospital's war trauma and emergency center.Methods Data were collected from 133 patients who received universal red blood cell transfusion in the war trauma center of our hospi-tal from January 2016 to December 2024.The basic information,universal red blood cell transfusion volume,compatible blood components,transfusion volume,blood routine(Hb,Hct),liver and kidney function(ALT,AST,TBil,DBil,cre-atinine,etc.)and coagulation function(PT,APTT,Fib,etc.)before and after transfusion were retrospectively analyzed.Results Among the 133 patients who received a total of 374 units of universal red blood cells,the 24-hour survival rate was 62.4%(83/133).Spearman correlation analysis showed a positive correlation between shock index and universal red blood cell transfusion volume(r=0.283,P<0.05).Patients were stratified by universal red blood cell transfusion volume(≤3 U vs≥4 U).The low volume group had less homotypic red blood cell transfusion volume and total transfusion volume at different time points,and the difference was statistically significant:within 2 h[2(2,4)vs 4(3,7),P=0.033<0.05],0～24 h[6(4,9)vs 8(6,14),P=0.028<0.05],total transfusion volume[13(8,20)vs 19(12,35),P=0.021<0.05].No acute hemolytic transfusion reaction occurred within 24 hours after transfusion of universal red blood cell.Conclusion Universal red blood cells are safe for use in emergency treatment.Furthermore,the shock index combined with the volume of universal red blood cells transfused can predict subsequent transfusion requirements and enables the early reservation of compatible blood,thereby preventing delayed resuscitation.关键词
创伤/通用型红细胞/休克指数/紧急救治Key words
trauma/universal red blood cell/shock index/emergency treatment分类
临床医学引用本文复制引用
李津杞,周梅,王星怡,张睿,臧艳,查占山,钱宝华,顾海慧..通用型红细胞紧急抢救失血性休克患者的临床应用研究[J].中国输血杂志,2025,38(10):1320-1326,7.基金项目
国家自然科学基金面上项目(81970165) （81970165）
