中国输血杂志2025，Vol.38Issue(10)：1327-1333,7.DOI:10.13303/j.cjbt.issn.1004-549x.2025.10.005
严重创伤紧急救治阶段血液保障模式探讨
A blood supply model for the emergency care of severe trauma
摘要
Abstract
Objective To establish and validate a whole blood(WB)supply model,thereby providing practical experi-ence for the clinical application of WB in domestic trauma emergency care and informing the development of a wartime blood supply system for the military.Methods A"10×24"WB supply model was established by formulating blood collection protocols,storage standards,and transfusion criteria.Multiple WB samples were tested under specific storage conditions to assess key indicators at different time points,including red blood cell(RBC),white blood cell(WBC),and platelet counts,hemoglobin concentration,coagulation parameters(PT,APTT,TT,FIB),coagulation factor activity,throm-boelastography(TEG)parameters,and electrolyte levels.Additionally,clinical data from hemorrhagic patients who met the criteria for WB transfusion and were admitted between March and July 2024 were analyzed to evaluate WB transfusion vol-ume.Results RBC counts and hemoglobin levels remained stable in WB stored at 4℃for up to 10 days.However,plate-let counts and coagulation function(PT,APTT)significantly declined with prolonged storage,while potassium levels in-creased.From March to July 2024,the model was successfully applied to 23 patients with acute hemorrhage,with a median WB transfusion volume of 543 mL.A detailed case study of a severe traumatic hemorrhagic shock patient was reported,who was successfully treated with 5.5 units of refrigerated WB combined with component blood.Conclusion The"10×24"WB supply model demonstrated acceptable changes in critical quality parameters under strict management and a 10-day rotation cycle.This model effectively supports the treatment of acute hemorrhage and holds promise for integration into the future wartime blood supply system of the military.关键词
全血输注/创伤性休克/冷藏全血Key words
whole blood transfusion/traumatic shock/refrigerated whole blood分类
临床医学引用本文复制引用
胡松林,卫志远,黄高翔,刘丽娟,傅明玮,谭珺珂,李浩哲,李松涛..严重创伤紧急救治阶段血液保障模式探讨[J].中国输血杂志,2025,38(10):1327-1333,7.基金项目
联勤保障部队第九二四医院院内科技计划(GS2022CZ03) （GS2022CZ03）
