中国畜牧兽医2025，Vol.52Issue(11)：5063-5073,11.DOI:10.16431/j.cnki.1671-7236.2025.11.005
马胎盘滋养层细胞研究进展
Research Progress on Trophoblast Cells of Horse Placenta
摘要
Abstract
During the gestation period of equine animals,trophoblast cells play a crucial role in various physiological processes such as embryo implantation,vascular remodeling at the maternal-fetal interface,and the exchange of nutrients and gases between the mother and the fetus.Due to the long period of migration of equine embryos within the uterus,the author briefly described the biological significance of equine embryo trophoblast cells in embryo positioning,pregnancy recognition,and maintaining pregnancy.Through elaborating on the regulatory mechanisms of steroid hormones,growth factors,and immune cytokines on trophoblast cells,the aim is to reveal their effects on the biological activity of trophoblast cells.At present,the research on equine trophoblast cells is still not complete.In the future,it may be possible to utilize new technologies such as single-cell sequencing and organoid culture to reveal the developmental regulatory patterns of these cells.Meanwhile,through multi-omics analysis,biomarkers suitable for early pregnancy diagnosis were identified to enhance the survival rate and reproductive efficiency of equine embryos.Furthermore,based on the reproductive characteristics of equine animals,the application of targeted nutritional regulation strategies and immune intervention methods can provide new ideas for improving the reproductive performance of horses.关键词
马/滋养层细胞/早期妊娠/胎盘形成/调控机制Key words
horse/trophoblast cells/early pregnancy/placenta formation/regulatory mechanisms分类
农业科技引用本文复制引用
阿斯雅,斯琴,伊敏娜,温鑫,格日乐其木格..马胎盘滋养层细胞研究进展[J].中国畜牧兽医,2025,52(11):5063-5073,11.基金项目
内蒙古自然科学基金杰出青年项目(2023JQ12) （2023JQ12）
内蒙古自治区科技计划项目2023KPT0004) （）
国家自然科学基金项目(32460834) （32460834）
内蒙古自治区教育厅一流学科科研专项项目(YLXKZX-NND-026) （YLXKZX-NND-026）
中央引导地方项目(2022ZY0132) （2022ZY0132）
