中国畜牧杂志2025，Vol.61Issue(11)：1-7,7.DOI:10.19556/j.0258-7033.20241120-03
纳米颗粒在精液冷冻保存中的应用研究进展
Research Progress on the Application of Nanoparticles in Semen Cryopreservation
摘要
Abstract
Semen cryopreservation technology is a biotechnology that extends the survival time of sperm,holding significant application value in areas such as the expansion of superior livestock breeding,assisted reproductive technology,fertility preservation and the protection of genetic diversity.Despite its routine application in animal husbandry,the decline in sperm quality due to cryoinjury remains a major factor limiting the effective application of semen cryopreservation.Nanoparticles have high biocompatibility and antimicrobial activity,and are involved in various cellular biological processes such as autophagy,apoptosis,and lipid metabolism.In recent years,nanoparticles have been gradually applied to semen cryopreservation.This review article summarizes the current status of semen cryopreservation technology and systematically discusses the research progress of nanoparticles in semen cryopreservation from aspects including the types of nanoparticles,their physicochemical and biological characteristics,the mechanisms of action,and their improvement on sperm damage,with the aim to deeply analyze the protective effects of nanoparticles on cryopreserved sperm and provide new methods for the efficient application of semen cryopreservation technology.关键词
纳米颗粒/精子/冷冻保存Key words
Nanoparticles/Sperm/Cryopreservation分类
农业科技引用本文复制引用
冯紫琼,李俊,白佳琛,马妍,王定国,钟皓澜,刘昱成,万鹏程,傅祥伟..纳米颗粒在精液冷冻保存中的应用研究进展[J].中国畜牧杂志,2025,61(11):1-7,7.基金项目
中央引导地方科技发展资金项目(纳米颗粒3D、226Z7713G、2024FRD05031) （纳米颗粒3D、226Z7713G、2024FRD05031）
河北省自然科学基金项目(H2020206254) （H2020206254）
兵团科技发展专项(S2021BC505) （S2021BC505）
重点领域科技攻关项目(2024AB017) （2024AB017）
国家绒毛用羊产业技术体系(CARS-39-07) （CARS-39-07）
新疆"天山英才"培养计划(2022TSYCCX0124) （2022TSYCCX0124）
新疆"天池英才"培养计划 （）
