中国药房2025，Vol.36Issue(21)：2621-2626,6.DOI:10.6039/j.issn.1001-0408.2025.21.01
基于国际视角的我国儿童基本药物遴选策略初探
Preliminary exploration of the selection strategy for essential medicines for children in China from an international perspective
摘要
Abstract
OBJECTIVE To offer references and implementation paths for updating and enhancing the China's current essential medicines list system,formulating a specific list of essential medicines for children in China,promoting the research and development of pediatric medications,and improving the accessibility and safety of pediatric medications for children.METHODS Comparative and descriptive analysis was utilized to statistically analyze the classification,dosage forms,specifications,disease spectrum,and symbolic annotations of the 9th edition of the WHO Model List of Essential Medicines for Children(WHO EMLc).Differences were compared among WHO EMLc,the 2018 National Essential Medicines List(NEML),and five batches of the List of Encouraged R&D and Declaration of Pediatric Drugs issued by the National Health Commission from 2016 to 2024.The availability of drugs in the 9th edition of WHO EMLc in China was discussed.RESULTS&CONCLUSIONS The differences between the two lists were relatively substantial.A total of 101 drugs overlapped,accounting for 27.98%of the total number of drugs in the 9th edition of the WHO EMLc.Compared with the 2018 NEML,the 9th edition of the WHO EMLc showed notable advantages in the diversity of pediatric-appropriate drug types,dosage form adaptability,and specification precision.The List of Encouraged R&D and Declaration of Pediatric Drugs,to some extent,had filled the gap in China's pediatric medications,enriching the variety of drug types and dosage forms for children.However,nearly 80%of the drugs on the list were not yet marketed,still facing problems such as a low R&D conversion rate and insufficient policy incentive effects.It is recommended to establish a tiered and classified pediatric essential medicines list based on China's national conditions,drawing on the selection experience of the WHO and developed countries/regions;strengthen support for the R&D of appropriate pediatric dosage forms and specifications;implement policy preferences throughout the entire cycle of application,review and procurement;encourage evidence-based pediatric practices,accelerate the R&D,market launch,and selection processes of pediatric essential medicines,and ensure the accessibility of pediatric medicines.关键词
WHO儿童基本药物目录/国家基本药物目录/儿童用药/药物遴选Key words
WHO Model List of Essential Medicines for Children/National Essential Medicines List/pediatric medication/drug selection分类
医药卫生引用本文复制引用
孙云龙,赖欣,田磊..基于国际视角的我国儿童基本药物遴选策略初探[J].中国药房,2025,36(21):2621-2626,6.基金项目
国家自然科学基金项目(No.72274217) （No.72274217）
